(S)-1-N-Boc-2-(aminomethyl)pyrrolidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 119020-01-8 |
| Product name | (S)-1-N-Boc-2-(aminomethyl)pyrrolidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-1-N-Boc-2-(aminomethyl)pyrrolidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-1-N-Boc-2-(aminomethyl)pyrrolidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-1-N-Boc-2-(aminomethyl)pyrrolidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a chiral intermediate in the synthesis of antiviral or central nervous system drugs | Multi-step organic synthesis; commonly involved in amide bond formation or amino group protection/deprotection |
| Medicinal Chemistry | Used to construct bioactive molecular scaffolds containing a pyrrolidine moiety | Condensation with carboxylic acids, aldehydes, or ketones to build complex heterocyclic compounds |
| Organic Synthesis | Used as a chiral amine source for asymmetric catalysis or chiral induction | Participates in stereoselective reactions such as reductive amination and Michael addition |
| Peptide Drug Development | Used as a non-natural amino acid derivative incorporated into peptide chains | Coupled as a Boc-protected amino component in solid-phase or solution-phase peptide synthesis |
Manufacturing Quality Control of (S)-1-N-Boc-2-(aminomethyl)pyrrolidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210 nm, calibrated against certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment using a chiral stationary phase and UV detection, comparing retention times and peak areas of (S)- and (R)-enantiomers. |
| Residual Solvents | GC-FID | Identification and quantification of common organic solvents (e.g., THF, MeOH, EtOAc) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration measuring water via iodine-sulfur dioxide reaction in anhydrous methanol-based medium. |
| Heavy Metals | ICP-MS | Multi-element trace metal analysis (e.g., Pb, Cd, Ni, Fe) using inductively coupled plasma mass spectrometry after acid digestion. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residue by inductively coupled plasma optical emission spectrometry following microwave-assisted digestion. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., de-Boc product, diastereomers) using gradient reverse-phase HPLC. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation at 20 degC using sodium D-line (589 nm) in specified solvent and concentration to confirm chiral integrity. |
| Residual Hydrochloric Acid | Acid-Base Titration | Titration with standardized NaOH solution using phenolphthalein indicator to quantify free HCl from Boc deprotection side reactions. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution based on Mie scattering theory using a laser diffraction particle size analyzer. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms by filtration, membrane transfer to soybean-casein digest agar, and incubation per USP <61>. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined aqueous suspension (e.g., 1% w/v in water) using calibrated pH electrode per USP <791>. |
Technical Specifications of (S)-1-N-Boc-2-(aminomethyl)pyrrolidine
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78-82°C |
| Optical Rotation | +24.0 to +26.0° (c=1, in methanol) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-1-N-Boc-2-(aminomethyl)pyrrolidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-1-N-Boc-2-(aminomethyl)pyrrolidine
Safety Information of (S)-1-N-Boc-2-(aminomethyl)pyrrolidine
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of (S)-1-N-Boc-2-(aminomethyl)pyrrolidine
Industrial (S)-1-N-Boc-2-(aminomethyl)pyrrolidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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