4,6-Dihydroxypyrimidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1193-24-4 |
| Product name | 4,6-Dihydroxypyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4,6-Dihydroxypyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4,6-Dihydroxypyrimidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4,6-Dihydroxypyrimidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for antiviral drug synthesis | Used as a pyrimidine precursor in the construction of nucleoside analogues |
| Agrochemicals | Raw material for fungicide synthesis | Applied in the preparation of agricultural fungicides containing a pyrimidine ring structure |
| Dyes | Intermediate for functional dyes | Participates in coupling reactions of heterocyclic dye molecules |
| Fine chemicals | Organic synthesis intermediate | Employed in laboratory and industrial research on pyrimidine derivative synthesis |
Manufacturing Quality Control of 4,6-Dihydroxypyrimidine
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity Assay | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase column (e.g., C18) with a buffer-organic solvent mobile phase and a UV detector (e.g., 254 nm) to quantify the main component peak area for purity calculation. Suitable for high-sensitivity and high-resolution separation of impurities from the main component. |
| Assay (Content Determination) | HPLC External Standard Method / Potentiometric Titration | HPLC External Standard Method: A calibration curve is prepared using standard solutions of known concentration, and the sample content is calculated based on peak area. Potentiometric Titration: Utilizes its weak acidity by titrating with a standard alkaline solution in aqueous or non-aqueous medium, with the endpoint determined by a potential jump. |
| Related Substances (Impurity Testing) | HPLC Gradient Elution Method | Employs a gradient elution program to enhance separation of impurities. Impurity levels are controlled against predefined limits (e.g., individual impurity ≤0.5%, total impurities ≤1.0%) to ensure product safety. |
| Loss on Drying | Drying Method (Constant Weight at 105°C) | Sample is dried in an oven at 105°C until constant weight. The percentage weight loss is calculated to reflect moisture and volatile content, typically required to be ≤0.5%. |
| Sulfated Ash (Residue on Ignition) | High-Temperature Ashing Method (700–800°C) | Sample is charred and then subjected to high-temperature incineration. The remaining inorganic residue is weighed to evaluate inorganic impurities or catalyst residues, usually required to be ≤0.1%. |
| Heavy Metals | Thioacetamide Method (as per Chinese Pharmacopoeia) | In weakly acidic conditions, the sample solution reacts with thioacetamide to form a colored complex, which is compared with a standard lead solution to control total heavy metal content (e.g., ≤20 ppm). |
| Residual Solvents | Gas Chromatography (GC-FID / HS-GC) | Headspace or direct injection is used, with capillary column separation and FID detection to quantify common organic solvents (e.g., methanol, ethanol, DMF), in compliance with ICH Q3C limits. |
| Melting Point | Capillary Melting Point Apparatus | Sample is packed into a capillary tube and heated at a specified rate. The temperature range from initial to complete melting is recorded (literature value typically >300°C with decomposition), used for identification and preliminary purity assessment. |
| pH (Aqueous Solution) | pH Meter Method | A solution of defined concentration (e.g., 1%) is prepared, and pH is measured using a calibrated pH meter to reflect acid-base characteristics and assist in detecting acidic or basic impurities. |
| Structural Confirmation | Infrared Spectroscopy (IR), Nuclear Magnetic Resonance (NMR) | IR is used for functional group identification (e.g., hydroxyl, pyrimidine ring characteristic peaks); ¹H-NMR and ¹³C-NMR provide hydrogen and carbon environmental information to confirm molecular structure consistency. |
Technical Specifications of 4,6-Dihydroxypyrimidine
| Test Item | Specification |
|---|---|
| Appearance | Orange solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 275-279 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4,6-Dihydroxypyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4,6-Dihydroxypyrimidine
Packaging of 4,6-Dihydroxypyrimidine
Industrial 4,6-Dihydroxypyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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