L-Norvaline tert-butyl ester hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 119483-47-5 |
| Product name | L-Norvaline tert-butyl ester hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for L-Norvaline tert-butyl ester hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk L-Norvaline tert-butyl ester hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of L-Norvaline tert-butyl ester hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antibiotic drugs | Esterification of L-norvaline with tert-butanol under acidic conditions, followed by hydrochloride salt formation |
| Chemical Synthesis | Chiral intermediate in organic synthesis | Applied in asymmetric or stereoselective reactions to introduce a chiral center |
| Biotechnology | Synthesis of peptides and protein derivatives | Used as an amino acid derivative in solid-phase or solution-phase peptide synthesis |
Manufacturing Quality Control of L-Norvaline tert-butyl ester hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 200-220 nm based on peak area comparison to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., diastereomers, hydrolysis products) using gradient HPLC with UV detection. |
| Optical Rotation | [alpha]D | Measures specific optical rotation in solution using a polarimeter to confirm chiral integrity and enantiomeric purity. |
| Residual Solvents | GC-FID | Determines trace levels of process solvents (e.g., THF, DCM, tert-butanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Quantifies water via coulometric or volumetric titration using iodine-based redox reaction in anhydrous methanol/pyridine medium. |
| Heavy Metals | ICP-MS | Detects and quantifies elemental impurities (e.g., Pb, Cd, Ni, Fe) at sub-ppb levels using inductively coupled plasma mass spectrometry. |
| Chloride Content | Potentiometric Titration | Measures chloride ions by titration with silver nitrate using a silver indicator electrode and reference electrode. |
| Residue on Ignition | Gravimetric Analysis | Determines non-volatile inorganic residue after high-temperature ashing (500-600 C) and weighing. |
| pH of Solution | pH Meter | Measures hydrogen ion activity in aqueous suspension (1% w/v) using calibrated glass electrode pH meter. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size distribution by measuring angular scattering pattern of laser beam passing through dispersed sample. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method under controlled heating rate. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic mesophilic microorganisms and detects specified pathogens (e.g., E. coli, S. aureus) by filtration, culture, and colony enumeration. |
Technical Specifications of L-Norvaline tert-butyl ester hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 75–79°C |
| Optical Rotation | +5.0° to +8.0° (c=1, in 6M HCl) |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of L-Norvaline tert-butyl ester hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of L-Norvaline tert-butyl ester hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of L-Norvaline tert-butyl ester hydrochloride
Industrial L-Norvaline tert-butyl ester hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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