2,4-DIAMINO-5-FLUOROQUINAZOLINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 119584-70-2 |
| Product name | 2,4-DIAMINO-5-FLUOROQUINAZOLINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,4-DIAMINO-5-FLUOROQUINAZOLINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,4-DIAMINO-5-FLUOROQUINAZOLINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,4-DIAMINO-5-FLUOROQUINAZOLINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for anticancer drugs, used in the synthesis of targeted kinase inhibitors (e.g., EGFR inhibitors) | Multi-step organic synthesis, including quinazoline ring construction, selective fluorination, and amino protection/deprotection |
| Pharmaceuticals | Lead compound scaffold in antibacterial drug research | Applied in molecular docking and structure–activity relationship (SAR) studies to optimize antibacterial activity of quinazoline derivatives |
| Research | Functionalized core structure for fluorescent probe development | Sulfonation or coupling reactions introduce fluorescent moieties for bioimaging and intracellular target detection |
Manufacturing Quality Control of 2,4-DIAMINO-5-FLUOROQUINAZOLINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-DAD | Identifies and quantifies impurities by retention time and UV spectral matching using diode-array detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone) via gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration using iodine generation in pyridine-methanol buffer. |
| Heavy Metals | ICP-MS | Quantifies Pb, Cd, Hg, As, and other heavy metals at sub-ppb levels using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after anion exchange separation. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after high-temperature combustion of sample with sulfuric acid pretreatment. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid phase transition using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and homogeneity against established reference standard under controlled lighting. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dry or wet dispersion using Mie scattering theory. |
| pH of Aqueous Suspension | pH Meter | Determines pH of a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic mesophilic microorganisms by filtration, membrane transfer to culture media, and colony enumeration. |
Technical Specifications of 2,4-DIAMINO-5-FLUOROQUINAZOLINE
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 248–252°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,4-DIAMINO-5-FLUOROQUINAZOLINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,4-DIAMINO-5-FLUOROQUINAZOLINE
Safety Information of 2,4-DIAMINO-5-FLUOROQUINAZOLINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2,4-DIAMINO-5-FLUOROQUINAZOLINE
Industrial 2,4-DIAMINO-5-FLUOROQUINAZOLINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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