3,4-Dihydro-2H-isoquinolin-1-one Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1196-38-9 |
| Product name | 3,4-Dihydro-2H-isoquinolin-1-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3,4-Dihydro-2H-isoquinolin-1-one
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3,4-Dihydro-2H-isoquinolin-1-one Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3,4-Dihydro-2H-isoquinolin-1-one
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antiplatelet agents (e.g., ticagrelor analogues) and dopamine receptor modulators | C–H activation coupling with aryl halides under palladium catalysis; or N-alkylation followed by cyclization to construct the isoquinolone scaffold |
| Pesticides | Structural building block for insecticides and plant growth regulators | Participates in heterocycle construction reactions, such as condensation with ethyl chloroacetate to prepare biologically active N-substituted derivatives |
| Materials Science | Building block for hole-transport materials in organic light-emitting diodes (OLEDs) | Suzuki or Buchwald–Hartwig coupling to introduce conjugated groups (e.g., carbazole, triphenylamine), forming thermally stable hole-transport layers |
| Dyes & Pigments | Core heterocyclic scaffold for high-performance fluorescent dyes | Bromination followed by coupling with fluorescein- or coumarin-based compounds to extend conjugation and enhance fluorescence quantum yield |
Manufacturing Quality Control of 3,4-Dihydro-2H-isoquinolin-1-one
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220-254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification and reporting of individual impurities above identification threshold. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, ethyl acetate) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generated electrochemically to react stoichiometrically with water in the sample. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using isotopic detection with high sensitivity and low detection limits. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against chloride standard calibration curve. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 700-800 C followed by sulfuric acid treatment and final weighing of residual inorganic ash. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using calibrated capillary apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passed through a solution, indicating chiral purity and identity. |
| Loss on Drying | Thermogravimetric Analysis | Weight loss measured after drying at 105 C for 2 hours under vacuum or nitrogen, reflecting volatile content and moisture. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode per USP <791>. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to determine volume-based particle size distribution in dispersed dry or wet sample. |
Technical Specifications of 3,4-Dihydro-2H-isoquinolin-1-one
| Test Item | Specification |
|---|---|
| Appearance | Light yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 128–132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3,4-Dihydro-2H-isoquinolin-1-one
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3,4-Dihydro-2H-isoquinolin-1-one
Safety Information of 3,4-Dihydro-2H-isoquinolin-1-one
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3,4-Dihydro-2H-isoquinolin-1-one
Industrial 3,4-Dihydro-2H-isoquinolin-1-one Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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