2-Bromo-4-methoxypyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 89488-29-9 |
| Product name | 2-Bromo-4-methoxypyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Bromo-4-methoxypyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Bromo-4-methoxypyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Bromo-4-methoxypyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Construction of drug molecule scaffolds (e.g., kinase inhibitors, G protein-coupled receptor modulators) | Used as an electrophile in nucleophilic substitution reactions to introduce bromo groups or as a coupling precursor |
| Pharmaceuticals | Synthesis of intermediates for anticancer or anti-inflammatory drugs | Carbon–carbon bond formation via Suzuki or Stille coupling reactions |
| Chemical Synthesis | Preparation of 4-methoxy-2-pyridylboronic acid or 4-methoxy-2-pyridylzinc reagents | Halogen–metal exchange or reaction with organometallic reagents |
| Chemical Synthesis | Building block for organic synthesis | Functionalization of the pyridine ring |
Manufacturing Quality Control of 2-Bromo-4-methoxypyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities (e.g., isomers, dehalogenated or hydrolyzed by-products) via gradient HPLC separation and UV response. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, dichloromethane) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine-based reagent, based on stoichiometric reaction with water. |
| Heavy Metals | ICP-OES | Quantifies metals (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma optical emission spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700-800 C) and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of sample against specified criteria (white to off-white crystalline powder). |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light to confirm absence of chiral contamination (though compound is achiral, detects enantiomeric impurities if present). |
| pH of Aqueous Suspension | pH Meter | Determines acidity/basicity of saturated aqueous suspension using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of solid particles in suspension using Mie scattering theory and laser diffraction principle. |
Technical Specifications of 2-Bromo-4-methoxypyridine
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 68–72°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Bromo-4-methoxypyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Bromo-4-methoxypyridine
Packaging of 2-Bromo-4-methoxypyridine
Industrial 2-Bromo-4-methoxypyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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