China Factory Direct
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| CAS number | 89642-50-2 |
| Product name | 5-BROMO-2-NITROBENZONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of quinolone antibacterial agents (e.g., levofloxacin) | Prepared from 2-nitro-5-bromobenzonitrile via reduction, fluorination, and other reaction steps to construct the drug’s core scaffold |
| Chemicals | Organic synthesis intermediate for heterocyclic compound preparation | Used as a starting material in coupling or cyclization reactions to build complex benzoheterocyclic structures |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, based on peak area comparison against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification and reporting of individual impurities above threshold limits per ICH Q3A. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common solvents (e.g., acetone, methanol, toluene) based on retention time and calibration curves. |
| Moisture Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine water content via stoichiometric reaction with water. |
| Inorganic Halides (Br-) | Ion Chromatography (IC) | Separation of bromide ions on an anion-exchange column with conductivity detection, calibrated against sodium bromide standards. |
| Heavy Metals | ICP-OES | Multi-element detection after acid digestion using inductively coupled plasma optical emission spectroscopy; total metals reported as Pb, Cd, Hg, As equivalents. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 700-750 C followed by sulfuric acid treatment and final weighing of residual inorganic ash. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary apparatus per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via laser scattering to report D10, D50, D90 values per ISO 13320. |
| Bulk Density | ASTM D1895 Method A | Measurement of mass per unit volume for freely settled powder in a standardized cylinder. |
| Organic Volatile Impurities (OVI) | GC-MS | Targeted and non-targeted screening using gas chromatography-mass spectrometry for structurally related volatile degradants or process residuals. |
| Chloride Content | Potentiometric Titration with AgNO3 | Titration with silver nitrate using silver indicator electrode to detect endpoint corresponding to AgCl precipitation. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 124–128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.