3'-Amino-2'-hydroxyacetophenone hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 90005-55-3 |
| Product name | 3'-Amino-2'-hydroxyacetophenone hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3'-Amino-2'-hydroxyacetophenone hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3'-Amino-2'-hydroxyacetophenone hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3'-Amino-2'-hydroxyacetophenone hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for the synthesis of the antiallergic drug olopatadine | Undergoes nucleophilic substitution with ethyl 2-chloropropionate under basic conditions, followed by cyclization and hydrolysis to produce olopatadine |
| Pharmaceutical Intermediates | Candidate intermediate for selective 5-HT₂C receptor agonists | Serves as an aromatic ring building block in multi-step syntheses, including Pd-catalyzed cross-coupling and reductive amination |
| Pesticide R&D | Structural motif under investigation for novel insecticides or plant growth regulators | Used in laboratory-scale synthesis of bioactive molecules containing benzoxazole or quinoline scaffolds; structural optimization is ongoing |
Manufacturing Quality Control of 3'-Amino-2'-hydroxyacetophenone hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or threshold reporting. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine reagent to quantify water content based on stoichiometric reaction with iodine and sulfur dioxide in pyridine/methanol medium. |
| Residue on Ignition | Gravimetric Analysis | Heating sample at 750 C to constant weight and measuring non-volatile inorganic residue as percentage of original mass. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column with conductivity detection, calibrated against NaCl standards. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element detection after acid digestion by inductively coupled plasma mass spectrometry with isotopic resolution and internal standard correction. |
| pH (1% aqueous solution) | Potentiometric pH Measurement | Measurement of hydrogen ion activity in a 1% w/v aqueous solution using calibrated glass electrode and pH meter. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, observed visually under controlled heating rate. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, used to assess chiral purity and identity. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Mass loss measured under controlled heating (105 C, 2 h) in air, reported as percentage of initial weight. |
| Sulfated Ash | Gravimetric Analysis | Sample charred, treated with sulfuric acid, ignited at 700 C, and residual ash weighed as sulfate-complexed inorganic content. |
| Microbial Limits | Membrane Filtration & Culture | Enumeration of aerobic mesophilic bacteria and fungi via filtration, membrane transfer to selective agar media, and colony counting after incubation. |
Technical Specifications of 3'-Amino-2'-hydroxyacetophenone hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 145-149°C |
| Identification (NMR) | Conforms to reference standard |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3'-Amino-2'-hydroxyacetophenone hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3'-Amino-2'-hydroxyacetophenone hydrochloride
Safety Information of 3'-Amino-2'-hydroxyacetophenone hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3'-Amino-2'-hydroxyacetophenone hydrochloride
Industrial 3'-Amino-2'-hydroxyacetophenone hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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