Hyaluronidase Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 9001-54-1 |
| Product name | Hyaluronidase |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Hyaluronidase
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Hyaluronidase Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Hyaluronidase
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Dissolving glycosaminoglycans for treating wounds, inflammation, etc. | Enzyme-catalyzed reaction |
| Medical Devices | Degrading hyaluronic acid to enhance drug absorption | Enzyme-linked immunosorbent assay (ELISA) |
| Biotechnology | Cell dissociation and tissue dispersion | Enzymatic digestion |
| Research | Cell biology and molecular biology studies | Enzyme activity assay |
Manufacturing Quality Control of Hyaluronidase
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Enzyme Activity | Spectrophotometric Assay (UV-Vis) | Measures hydrolysis rate of hyaluronic acid substrate by monitoring absorbance change at 232 nm due to unsaturated bond formation. |
| Protein Content | Bradford Assay | Quantifies protein concentration based on Coomassie Brilliant Blue G-250 dye binding to basic and aromatic amino acid residues. |
| Residual Host Cell Proteins | ELISA | Detects trace host cell proteins using antigen-specific antibodies and enzymatic colorimetric signal amplification. |
| Residual DNA | Fluorometric Assay (PicoGreen) | Binds double-stranded DNA with fluorescent dye; fluorescence intensity proportional to DNA concentration. |
| Heavy Metals | ICP-OES | Atomizes sample and measures element-specific emission spectra for simultaneous multi-element quantification. |
| pH | Potentiometric Titration | Determines hydrogen ion activity using calibrated pH electrode in aqueous solution. |
| Moisture Content | Karl Fischer Titration | Quantifies water via stoichiometric reaction between iodine, sulfur dioxide, and water in methanol-based reagent. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against standard reference under controlled lighting conditions. |
| Microbial Contamination | Membrane Filtration and Plate Count | Filters sample, incubates membrane on appropriate agar, and enumerates colony-forming units after incubation. |
| Endotoxin Level | LAL Assay | Measures endotoxin-induced coagulation cascade in Limulus amebocyte lysate, detected turbidimetrically or chromogenically. |
| Specific Activity | Enzyme Activity / Protein Content Calculation | Ratio of measured enzyme activity (U/mg) to total protein concentration, indicating functional purity. |
| Related Substances | RP-HPLC | Separates impurities and degradation products using reversed-phase C18 column and UV detection at 280 nm. |
Technical Specifications of Hyaluronidase
| Test Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.5% |
| Optical Rotation | -20° to -30° (c=1, in 0.1 M phosphate buffer, pH 7.0) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Hyaluronidase
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of Hyaluronidase
Industrial Hyaluronidase Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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