Tocofersolan Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 9002-96-4 |
| Product name | Tocofersolan |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Tocofersolan
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Tocofersolan Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Tocofersolan
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical excipient to enhance the aqueous solubility and bioavailability of lipophilic drugs | Prepared via esterification of vitamin E with polyethylene glycol succinate to improve drug dissolution and absorption in vivo |
| Cosmetics | Used as an antioxidant and skin-moisturizing agent to enhance product stability | Incorporated into emulsions, creams, and other formulations, leveraging its hydrophilic-lipophilic balance (HLB) to improve skin feel and antioxidant efficacy |
| Food Additives | Used as a food antioxidant to extend shelf life | Added to oils or high-fat foods to inhibit oxidative degradation through free-radical scavenging |
| Biomaterials | Applied for surface modification of nanocarriers (e.g., liposomes, micelles) to enhance stability and targeting capability | Leverages its amphiphilic structure to self-assemble into micelles in aqueous media or coat nanoparticle surfaces, optimizing drug delivery systems |
Manufacturing Quality Control of Tocofersolan
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color and state of the sample under natural or standard lighting. It should be a viscous liquid ranging from light yellow to amber, with no visible foreign matter. |
| Acid Value | Acid-Base Titration | Titrate free acids in the sample using a standardized potassium hydroxide ethanol solution. The acid value is expressed as milligrams of KOH consumed per gram of sample, reflecting the degree of esterification and potential degradation. |
| Hydroxyl Value | Acetylation-Titration Method | The sample reacts with acetic anhydride to form esters. After hydrolysis, the liberated acetic acid is titrated with a standard alkaline solution to calculate hydroxyl number, used to evaluate the hydroxyl content at the terminal ends of PEG chains. |
| Saponification Value | Saponification-Back Titration Method | The sample is heated with excess KOH ethanol solution for saponification. The residual alkali is back-titrated with a standard acid solution. The saponification value indicates the total amount of KOH required to completely saponify the sample, reflecting total ester content. |
| Water Content | Karl Fischer Titration | Quantitative determination of water based on the reaction of iodine with sulfur dioxide in a pyridine/methanol system. Suitable for trace moisture analysis. |
| Molecular Weight Distribution | Gel Permeation Chromatography (GPC) or SEC-HPLC | Different molecular weight components are separated through a chromatographic column, and detected by a refractive index detector to determine molecular weights (e.g., Mn, Mw) and polydispersity index (PDI), assessing polymer uniformity. |
| Identification (Structural Confirmation) | Fourier Transform Infrared Spectroscopy (FTIR) | Record the infrared absorption spectrum of the sample and compare it with reference spectra to confirm characteristic functional groups (e.g., ester bonds, aromatic rings, PEG segments). |
| Vitamin E Content | High-Performance Liquid Chromatography (HPLC-UV) | Using a reversed-phase C18 column and UV detector (around 290 nm), determine the content of free or total vitamin E to assess raw material purity. |
| Polyethylene Glycol (PEG) Content | HPLC-ELSD or GPC | Determine the relative content of PEG segments using Evaporative Light Scattering Detector (ELSD) or GPC to evaluate consistency of copolymer composition. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Digest the sample and analyze for residual heavy metals such as lead, arsenic, mercury, and cadmium. Must comply with pharmacopeial limits for pharmaceutical excipients (e.g., ≤10 ppm). |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents possibly remaining from manufacturing (e.g., toluene, ethanol) according to ICH guidelines, using an FID detector. |
| Microbial Limits | Microbial Limit Test | Perform tests for total aerobic microbial count, mold and yeast count, and specified microorganisms (e.g., *Escherichia coli*) in accordance with the Chinese Pharmacopoeia or USP. |
Technical Specifications of Tocofersolan
| Test Item | Specification |
|---|---|
| Appearance | Pale yellow to light amber viscous liquid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Acid Value (mg KOH/g) | <=5.0 mg KOH/g |
| Residue on Ignition | <=0.3% |
| Odor | Characteristic mild odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Tocofersolan
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of Tocofersolan
Industrial Tocofersolan Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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