Chymotrypsin Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 9004-07-3 |
| Product name | Chymotrypsin |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Chymotrypsin
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Chymotrypsin Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Chymotrypsin
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Treatment of ocular diseases | Used in ophthalmic surgery to degrade intraocular inflammatory tissue or clear vitreous hemorrhage |
| Biotechnology | Protein hydrolysis | Applied in vitro to cleave specific peptide bonds, particularly at the carboxyl side of aromatic amino acids (e.g., phenylalanine, tyrosine) |
| Medical aesthetics | Anti-inflammatory and anti-edema effects | Administered via local injection to promote absorption of inflammation and reduce postoperative swelling |
| Pharmaceutical manufacturing | Active pharmaceutical ingredient | Formulated as a proteolytic drug to improve microcirculation and remove necrotic tissue |
| Food industry | Protein modification | Employed in specific food processing operations to hydrolyze proteins and enhance texture or functional properties |
| Research | Molecular biology studies | Utilized for site-specific proteolysis in protein sequencing or structural analysis |
Manufacturing Quality Control of Chymotrypsin
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Enzyme Activity | Spectrophotometric Assay (UV-Vis) | Measures hydrolysis rate of synthetic substrate (e.g., N-benzoyl-L-tyrosine ethyl ester) at 253 nm; activity calculated from initial velocity of product formation. |
| Protein Content | Lowry Assay | Quantifies protein based on Cu2+ complex formation with peptide bonds and aromatic residues, followed by Folin-Ciocalteu reagent color development. |
| Purity (by SDS-PAGE) | Electrophoresis (SDS-PAGE) | Separates proteins by molecular weight under denaturing conditions; purity assessed via band intensity and absence of contaminating bands. |
| Residual Moisture | Karl Fischer Titration | Determines water content via stoichiometric reaction between water, iodine, sulfur dioxide, and base in methanol/pyridine solvent. |
| pH | Potentiometric Measurement (pH meter) | Measures hydrogen ion activity in aqueous solution using calibrated glass electrode and reference electrode. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Quantifies trace metal elements by atomizing and ionizing sample in plasma, then detecting mass-to-charge ratios with high sensitivity. |
| Microbial Contamination | Membrane Filtration and Colony Counting | Filters sample through sterile membrane, incubates on appropriate agar media, and enumerates viable aerobic bacteria and fungi. |
| Endotoxin Level | Limulus Amebocyte Lysate (LAL) Assay | Detects bacterial endotoxins via enzymatic cascade triggered by endotoxin in lysate from horseshoe crab blood cells. |
| Specific Absorbance (A1% 280 nm) | UV-Vis Spectrophotometry | Measures absorbance at 280 nm of a 1% (w/v) solution; used to assess consistency of protein chromophore content. |
| Residual Solvents | Gas Chromatography (GC-FID) | Separates and quantifies volatile organic solvents using capillary column and flame ionization detection. |
| Bioburden (Total Viable Count) | Plate Count Agar (PCA) Method | Dilutes sample, spreads on PCA plates, incubates at 30-35 C for 48-72 h, and counts colony-forming units. |
| Sterility | Direct Inoculation into Culture Media | Inoculates sample into fluid thioglycollate and soybean-casein digest media, incubates for 14 days, and observes for microbial growth. |
Technical Specifications of Chymotrypsin
| Test Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.5% |
| Optical Rotation | -25° to -35° (c=1, 0.1N HCl) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Chymotrypsin
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of Chymotrypsin
Industrial Chymotrypsin Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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