Hydroxypropyl methyl cellulose Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 9004-65-3 |
| Product name | Hydroxypropyl methyl cellulose |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeMaterial GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Hydroxypropyl methyl cellulose
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Hydroxypropyl methyl cellulose Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Hydroxypropyl methyl cellulose
| Industry | Applications | Process |
|---|---|---|
| Construction & Building Materials | Thickener and water-retention agent for cement-based mortars; improves workability | Add 0.1–0.5 wt% to dry-mix mortars to suppress excessive moisture loss, enhancing bond strength and sag resistance |
| Pharmaceuticals | Tablet binder, sustained-release matrix former, thickener for ophthalmic formulations | Use 2–5% HPMC aqueous solution as a binder in wet granulation; employ K4M/K100M grades in oral sustained-release tablets to control drug release rate; incorporate at 0.3–1.0% concentration in ophthalmic solutions to provide mucoadhesive viscosity and extended residence time |
| Food | Thickener, stabilizer, and film-forming agent (INS 464) | Add 0.1–0.3% to dairy alternatives (e.g., vegetable-based whipping cream) to prevent phase separation; prepare 1–3% aqueous solutions for coating vegetarian sausage casings or confectionery, followed by drying to form films |
| Personal Care | Thickener for shampoos and body washes; suspending stabilizer for toothpaste | Incorporate 0.3–1.0% into surfactant systems to impart pseudoplastic rheology; add 0.4–0.8% to toothpaste to suspend abrasives (e.g., calcium carbonate) and modulate extrusion behavior |
| Coatings | Rheology modifier for waterborne latex paints; pigment dispersion stabilizer | Add 0.2–0.6% (based on total formulation) post-emulsion polymerization to deliver high-shear thinning and low-shear structural viscosity, minimizing settling and spattering |
Manufacturing Quality Control of Hydroxypropyl methyl cellulose
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Place the sample on a white background and observe its color and physical state. It should be white or off-white powder, free from visible foreign matter. |
| Identification | Fourier Transform Infrared Spectroscopy (FTIR) | Obtain the infrared absorption spectrum of the sample using an FTIR spectrometer and compare it with the reference spectrum to confirm consistency of characteristic molecular structure peaks. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry the sample at 105°C for 2 hours and measure the percentage weight loss to evaluate moisture and volatile content. |
| Residue on Ignition (Ash Content) | Ignition Residue Method | Ignite the sample at high temperature (approximately 600–800°C) until constant weight is achieved, then determine the percentage weight of inorganic residue. |
| Degree of Substitution (Methoxy Content) | Acid Hydrolysis-Gas Chromatography or Titration Method | Release methoxy groups via acid hydrolysis, then quantify methoxy content using gas chromatography (GC) or titration to calculate the degree of substitution. |
| Hydroxypropoxy Content | Gas Chromatography (GC) or Iodometric Method | After oxidation reaction, measure the generated propylene glycol derivatives using GC or iodometric titration to determine hydroxypropoxy content. |
| pH Value | pH Meter Method | Prepare a 1%–2% aqueous solution of HPMC and measure its pH using a calibrated pH meter. The value should typically fall within the range of 5.0–8.0. |
| Viscosity | Rotational Viscometry (e.g., Brookfield) | Measure the viscosity (in mPa·s) of a defined concentration (commonly 2%) HPMC aqueous solution at a specified temperature (e.g., 20°C) using a rotational viscometer. |
| Particle Size Distribution | Laser Diffraction or Sieve Analysis | Analyze particle size range and distribution using a laser diffraction particle size analyzer or standard sieves. |
| Microbial Limits | Microbial Limits Testing (Pharmacopoeial Method) | Perform tests according to the requirements of the Chinese Pharmacopoeia or USP, including total aerobic microbial count, total mold and yeast count, and specified pathogens (e.g., *E. coli*). |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After digesting the sample, determine the levels of heavy metal elements such as lead, arsenic, cadmium, and mercury to ensure compliance with pharmacopeial limits for pharmaceutical excipients. |
| Solubility | Solubility Test | Observe the solubility of HPMC in cold water (forms a clear or slightly opalescent colloidal solution), noting that it is insoluble in hot water. |
Technical Specifications of Hydroxypropyl methyl cellulose
| Test Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=1.0% |
| Solubility | Freely soluble in cold water; forms viscous colloidal solution |
| Color (APHA/Pt-Co) | <=100 |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Hydroxypropyl methyl cellulose
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of Hydroxypropyl methyl cellulose
Industrial Hydroxypropyl methyl cellulose Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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