Hydroxyethyl starch Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 9005-27-0 |
| Product name | Hydroxyethyl starch |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Hydroxyethyl starch
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Hydroxyethyl starch Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Hydroxyethyl starch
| Industry | Application | Process Function |
|---|---|---|
| Pharmaceuticals | Plasma substitute for blood volume expansion | Regulates blood osmotic pressure |
| Pharmaceuticals | Excipient in pharmaceutical formulations | Enhances drug stability |
| Cosmetics | Humectant | Provides skin moisturization |
| Food Industry | Food additive for texture improvement | Thickener |
| Pulp & Paper | Paper strength enhancer | Improves paper tensile strength |
| Textiles | Textile sizing agent | Enhances inter-fiber adhesion |
| Oilfield Chemistry | Drilling fluid additive | Increases drilling fluid viscosity and stability |
Manufacturing Quality Control of Hydroxyethyl starch
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color and physical state of the sample; typically a white to off-white amorphous powder, free from visible foreign matter. |
| Identification | Infrared Spectroscopy (IR) | Compare the sample spectrum with a reference standard spectrum; confirm molecular structure by characteristic absorption peaks (e.g., O-H, C-O-C). |
| Weight-Average Molecular Weight (Mw) | Gel Permeation Chromatography (GPC) or Size Exclusion Chromatography (SEC) | Calibrate using standard reference materials; measure the hydrodynamic volume of HES molecules to calculate weight-average (Mw) and number-average (Mn) molecular weights. |
| Molecular Weight Distribution (PDI) | Gel Permeation Chromatography (GPC) | Calculate the ratio of Mw/Mn (weight-average to number-average molecular weight) to assess uniformity of molecular weight distribution (polydispersity index). |
| Degree of Substitution (DS) | Proton Nuclear Magnetic Resonance Spectroscopy (¹H-NMR) | Calculate the average number of substituted moles per glucose unit by comparing the integral areas of the H-1 peak in the glucose unit and the -CH₂- peak of the hydroxyethyl group. |
| Molar Substitution (MS) | Proton Nuclear Magnetic Resonance Spectroscopy (¹H-NMR) | Determine the average molar amount of ethylene oxide introduced per glucose unit; reflects the extent of hydroxyethylation, influencing metabolic stability in vivo. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry the sample at a specified temperature (e.g., 105 °C) to constant weight; calculate percentage weight loss to control moisture content. |
| Sulfated Ash | Sulfated Ash Test | Ignite the sample at high temperature (approx. 600–800 °C), then weigh the residue to evaluate inorganic impurity content. |
| pH Value | pH Meter Method | Prepare an aqueous solution of defined concentration (e.g., 5%), measure acidity/alkalinity using a calibrated pH meter; typically within the range of 4.0–7.0. |
| Solution Clarity and Color | Visual Comparison or Spectrophotometry | Inspect solution visually for clarity after preparation, or measure absorbance at specific wavelengths (e.g., 400–600 nm) to control coloration. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Detect residual heavy metals such as lead, arsenic, mercury, and cadmium to ensure compliance with pharmacopoeial limits. |
| Bacterial Endotoxins | Limulus Amebocyte Lysate Test (LAL) | Utilize lysate from horseshoe crab blood cells that reacts with endotoxins to form gel or produce color change; quantitatively determine bacterial endotoxin levels (typically <0.5 EU/mg). |
| Microbial Limits | Microbiological Culture Method | Perform tests according to pharmacopoeial requirements for total aerobic microbial count, mold and yeast count, and specified microorganisms (e.g., Escherichia coli). |
| Visible Particulates | Visual Inspection (Light Check) or Automated Visible Particle Detection | Visually inspect or use automated instruments under specified lighting conditions to detect visible particles such as fibers or black specks in solution. |
| Assay (in terms of glucose units) | Reducing Sugar Assay after Acid Hydrolysis (e.g., DNS method) or High-Performance Liquid Chromatography (HPLC) | Hydrolyze HES to glucose, then measure total sugar content to assess product purity and batch-to-batch consistency. |
Technical Specifications of Hydroxyethyl starch
| Test Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.5% |
| Solubility | Freely soluble in water; insoluble in ethanol and acetone |
| Odor | Characteristic, faintly sweet |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Hydroxyethyl starch
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of Hydroxyethyl starch
Industrial Hydroxyethyl starch Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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