α-galactosidase Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 9025-35-8 |
| Product name | α-galactosidase |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for α-galactosidase
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk α-galactosidase Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of α-galactosidase
| Industry | Application | Process |
|---|---|---|
| Food Industry | Reduces oligosaccharide (raffinose, stachyose) content in legume-based products to minimize post-consumption gastrointestinal flatulence | Added to soy milk or soy powder and enzymatically hydrolyzed at 37–50°C and pH 6.0–7.0 for 30–120 minutes |
| Feed Industry | Improves digestibility and nutritional value of plant-based protein feeds such as soybean meal and rapeseed meal | Sprayed onto compound feed either before or after pelleting; degrades α-galactosidic antinutritional factors in the animal gastrointestinal tract (pH 4.5–6.5) |
| Pharmaceutical Industry | Used in quality control and activity assay during enzyme replacement therapy (ERT) drug manufacturing for Fabry disease | Serves as a reference enzyme for in vitro activity unit calibration of recombinant α-galactosidase formulations (e.g., agalsidase beta), per USP/EP pharmacopoeial methods |
| Biotechnology | Applied in glycomics research for specific removal of terminal α-galactose residues from glycoproteins and glycolipids | Incubated for several hours at 37°C in buffer (e.g., 50 mM sodium acetate, pH 4.5–5.5) to support N-glycan structural analysis |
| Diagnostics | Key component in assays for measuring α-galactosidase A activity in urine or leukocytes to support Fabry disease screening | Reacted with synthetic substrate 4-methylumbelliferyl-α-D-galactopyranoside (4-MUG); enzymatic product quantified fluorometrically |
Manufacturing Quality Control of α-galactosidase
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Enzyme Activity | Spectrophotometric Assay (pNPG substrate) | Hydrolysis of p-nitrophenyl-alpha-D-galactopyranoside releases p-nitrophenol, measured at 405 nm absorbance. |
| Protein Concentration | Bradford Assay | Binding of Coomassie Brilliant Blue G-250 dye to protein causes spectral shift, quantified at 595 nm. |
| Purity (SDS-PAGE) | Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis | Separation by molecular weight under denaturing conditions; purity assessed via single dominant band. |
| Residual Host Cell Proteins | ELISA | Antibody-based detection and quantification of host cell protein contaminants using specific antibodies. |
| Residual DNA | Fluorometric Assay (PicoGreen) | DNA-bound PicoGreen dye exhibits enhanced fluorescence proportional to double-stranded DNA concentration. |
| Microbial Contamination | Membrane Filtration and Colony Counting | Sample filtration followed by incubation on agar media; enumeration of viable aerobic mesophilic microorganisms. |
| Endotoxin Level | Kinetic Turbidimetric LAL Assay | Endotoxin-induced coagulation cascade in Limulus amebocyte lysate produces turbidity measured over time. |
| Moisture Content | Karl Fischer Titration | Iodine reacts stoichiometrically with water in methanol-based solvent; endpoint detected electrometrically. |
| pH | Potentiometric Measurement | Hydrogen ion activity determined using calibrated glass electrode and reference electrode in aqueous solution. |
| Heavy Metals | ICP-OES | Atomization and excitation of metals in plasma; elemental quantification via characteristic emission wavelengths. |
| Specific Activity | Calculated from Enzyme Activity and Protein Concentration | Ratio of enzyme activity units (U/mg) to total protein concentration, indicating catalytic efficiency. |
| Sterility | Direct Inoculation into Culture Media | Sample introduced into fluid thioglycollate and soybean-casein digest media; incubated and observed for microbial growth. |
Technical Specifications of α-galactosidase
| Test Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.5% |
| Optical Rotation | -20.0 to -30.0 deg (c=1, H2O) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of α-galactosidase
| CAS/Product ID | *Required fields | |
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Packaging of α-galactosidase
Industrial α-galactosidase Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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