2-Fluoro-6-methylbenzoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 90259-27-1 |
| Product name | 2-Fluoro-6-methylbenzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Fluoro-6-methylbenzoic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Fluoro-6-methylbenzoic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Fluoro-6-methylbenzoic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for non-steroidal anti-inflammatory drugs (NSAIDs), e.g., flurbiprofen | Used as a key chiral intermediate in coupling, esterification, and reduction reactions for multi-step synthesis of the target active pharmaceutical ingredient (API) |
| Agrochemicals | Structural building block for novel herbicides and insecticides | Applied to construct fluorinated heterocyclic agrochemical molecules; active functional groups are introduced via condensation of acyl chlorides with amines |
| Materials | Synthetic precursor for liquid crystal monomers and organic light-emitting diode (OLED) functional materials | Used to incorporate rigid fluorinated aryl ring structures into target molecules via halogenation, coupling, or polymerization reactions, thereby tuning thermal stability and dielectric anisotropy |
Manufacturing Quality Control of 2-Fluoro-6-methylbenzoic acid
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Physical Form | Visual inspection, Melting point determination | Observe sample color and state (typically white to off-white crystalline powder), determine melting range (literature value ~115–120 °C) to assess purity and crystallinity. |
| Assay (Main Component) | High-Performance Liquid Chromatography (HPLC) | Use a C18 column with mobile phase of methanol-water or acetonitrile-phosphate buffer (e.g., pH 3.0), detect at UV 254 nm, quantify using external standard method; effectively separates impurities from the main component. |
| Related Substances (Impurity Profile) | HPLC (Gradient Elution) | Apply gradient elution to detect potential impurities such as unreacted starting materials (e.g., 2-fluorobenzoic acid, 6-methylbenzoic acid), fluorination by-products, and oxidative degradation products; acceptance limit typically ≤1.0%. |
| Fluorine Content | Ion Chromatography (IC) or Fluoride Ion-Selective Electrode | After alkaline fusion or hydrolysis, determine fluoride ion concentration via ion chromatography or potentiometric titration using a fluoride ion-selective electrode; ensure fluorine content matches theoretical value (theoretical F% ≈ 10.3%). |
| Moisture Content | Karl Fischer Titration | Determine trace moisture using volumetric or coulometric methods; control moisture level ≤0.5% to prevent hydrolysis or stability issues due to water of crystallization. |
| Residual Solvents | Gas Chromatography (GC) | Use DB-624 or PLOT column with headspace injection to detect residual organic solvents such as ethanol, ethyl acetate, and dichloromethane; comply with ICH Q3C guidelines. |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, measure levels of heavy metals such as lead, cadmium, mercury, and arsenic; typically require ≤10 ppm to meet pharmaceutical standards. |
| Acid Value / Purity (Titration) | Acid-Base Titration | Titrate carboxylic acid groups with standardized sodium hydroxide solution; calculate purity based on equivalent weight (1 mol acid ≈ 1 mol NaOH); suitable for rapid preliminary assessment. |
| Infrared Spectrum (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Compare with reference spectrum to confirm characteristic functional groups: O-H stretch of carboxylic acid (3000–2500 cm⁻¹), C=O (1680–1720 cm⁻¹), C-F (1200–1300 cm⁻¹), methyl C-H (2900–3000 cm⁻¹). |
| Nuclear Magnetic Resonance (¹H NMR / ¹³C NMR) | Nuclear Magnetic Resonance Spectroscopy | Dissolve in DMSO-d₆ or CDCl₃; confirm structure via chemical shifts and integration ratios (e.g., aromatic H, methyl H, carboxylic H); used for structural confirmation and impurity identification. |
| Polymorphic Form Analysis (if applicable) | X-Ray Powder Diffraction (XRPD) | If polymorphism exists, use XRPD patterns to verify consistency of crystal form and avoid differences in dissolution rate or stability due to polymorphic variation. |
Technical Specifications of 2-Fluoro-6-methylbenzoic acid
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 112-116°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Fluoro-6-methylbenzoic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Fluoro-6-methylbenzoic acid
Safety Information of 2-Fluoro-6-methylbenzoic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Fluoro-6-methylbenzoic acid
Industrial 2-Fluoro-6-methylbenzoic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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