NUCLEOSIDE PHOSPHORYLASE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 9030-21-1 |
| Product name | NUCLEOSIDE PHOSPHORYLASE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for NUCLEOSIDE PHOSPHORYLASE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk NUCLEOSIDE PHOSPHORYLASE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of NUCLEOSIDE PHOSPHORYLASE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Manufacture of vidarabine | Catalyzes the synthesis of 2'-deoxyguanosine from guanosine |
| Pharmaceutical R&D | Manufacture of ribavirin | Catalyzes the synthesis of nucleoside drug intermediates from guanosine |
| Biotechnology | Gene therapy | Enzyme replacement therapy (for research on purine nucleoside phosphorylase deficiency) |
| Diagnostic Industry | Production of diagnostic reagents | Used in detection of immune system–related disorders |
| Biotechnology | Nucleotide synthesis | Catalyzes the phosphorylation of purine nucleosides |
| Scientific Research | Enzyme kinetics studies | Investigates mechanisms of purine metabolism pathways |
Manufacturing Quality Control of NUCLEOSIDE PHOSPHORYLASE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Enzyme Activity | Spectrophotometric Assay (UV-Vis) | Measures rate of inosine cleavage by monitoring absorbance change at 290 nm due to hypoxanthine formation. |
| Protein Concentration | Bradford Assay | Based on Coomassie Brilliant Blue G-250 dye binding to basic and aromatic amino acid residues, causing spectral shift. |
| Purity (SDS-PAGE) | SDS-Polyacrylamide Gel Electrophoresis | Separates proteins by molecular weight under denaturing conditions; purity assessed via single band intensity. |
| Residual Host Cell Proteins | ELISA | Quantifies non-target proteins using antibody capture and enzymatic colorimetric detection. |
| Endotoxin Level | Limulus Amebocyte Lysate (LAL) Assay | Detects endotoxins via coagulation cascade activation in horseshoe crab lysate, measured turbidimetrically or chromogenically. |
| Residual DNA | Fluorometric DNA Quantitation (e.g., PicoGreen) | Uses fluorescent dye that selectively binds double-stranded DNA, with intensity proportional to DNA concentration. |
| Moisture Content | Karl Fischer Titration | Measures water content via stoichiometric reaction between water, iodine, sulfur dioxide, and pyridine/base in methanol. |
| pH | Potentiometric pH Measurement | Determines hydrogen ion activity using calibrated glass electrode and reference electrode in aqueous solution. |
| Heavy Metals | ICP-OES | Quantifies trace metal impurities by measuring element-specific atomic emission intensities after plasma atomization/excitation. |
| Bioburden | Membrane Filtration and Colony Counting | Captures viable microorganisms on filter membrane, followed by incubation and enumeration of colony-forming units. |
| Osmolality | Freezing Point Depression Osmometry | Determines solute concentration by measuring depression of freezing point relative to pure water. |
| Sterility | Direct Inoculation into Culture Media | Samples are aseptically transferred into fluid thioglycollate and soybean-casein digest media, then incubated and observed for microbial growth. |
Technical Specifications of NUCLEOSIDE PHOSPHORYLASE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.5% |
| Optical Rotation | -15.0 to -25.0 deg (c=1, H2O) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of NUCLEOSIDE PHOSPHORYLASE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of NUCLEOSIDE PHOSPHORYLASE
Industrial NUCLEOSIDE PHOSPHORYLASE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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