trans-4-Cyclohexyl-L-proline hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 90657-55-9 |
| Product name | trans-4-Cyclohexyl-L-proline hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for trans-4-Cyclohexyl-L-proline hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk trans-4-Cyclohexyl-L-proline hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of trans-4-Cyclohexyl-L-proline hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral building block for synthesizing active pharmaceutical ingredients (e.g., protease inhibitors) | Organic synthesis, chiral resolution, crystallization purification |
| Research & Development | Construction of complex chiral compounds or peptide analogs in laboratory studies | Solid-phase synthesis, solution-phase synthesis, chromatographic purification |
| Biochemistry | Amino acid derivative used for peptide modification or structural/functional studies of proteins | Enzymatic synthesis, chemical conjugation, analytical testing |
Manufacturing Quality Control of trans-4-Cyclohexyl-L-proline hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase; quantitation based on relative peak areas of trans-4-cyclohexyl-L-proline vs. D-isomer. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine reagent to determine trace water content based on stoichiometric reaction with water. |
| Residual Solvents | GC-FID | Gas chromatographic separation followed by flame ionization detection; quantitation against internal/external standards per ICH Q3C. |
| Heavy Metals | ICP-MS | Multi-element detection of Pb, Cd, Hg, As, and other regulated metals after acid digestion and matrix-matched calibration. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode; endpoint detected by potential change due to AgCl precipitation. |
| pH (1% w/v aqueous solution) | pH Meter Measurement | Direct measurement using calibrated pH electrode in a defined aqueous solution at 25 C. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or discoloration against established reference standards. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, using calibrated digital melting point instrument. |
| Specific Optical Rotation | [alpha]D Measurement | Measurement of rotation of plane-polarized light at 589 nm using sodium D-line, corrected for concentration and path length. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., diastereomers, dechlorinated analogs) using gradient HPLC. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after controlled high-temperature ashing (700-800 C) to assess inorganic ash content. |
Technical Specifications of trans-4-Cyclohexyl-L-proline hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 215-220°C |
| Optical Rotation | +15.0° to +17.0° (c=1, 6M HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of trans-4-Cyclohexyl-L-proline hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of trans-4-Cyclohexyl-L-proline hydrochloride
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of trans-4-Cyclohexyl-L-proline hydrochloride
Industrial trans-4-Cyclohexyl-L-proline hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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