China Factory Direct
|
|
| CAS number | 90748-01-9 |
| Product name | 4-HYDROXYMETHYL-PIPERIDINE HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a synthetic drug intermediate in the preparation of antidepressants and neuropsychiatric agents | Prepared via salt formation between 4-(hydroxymethyl)piperidine and hydrochloric acid; employed in subsequent condensation, alkylation, or cyclization reactions to construct complex molecular frameworks |
| Chemical Synthesis | Used as a chiral building block for constructing nitrogen-containing heterocyclic compounds | Applied in organic synthesis as an amino alcohol derivative, participating in reductive amination, Mitsunobu reactions, or serving as a ligand precursor |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities by retention time comparison and relative response factors. |
| Water Content | Karl Fischer Titration | Measures water via stoichiometric reaction between iodine, sulfur dioxide, and water in anhydrous methanol/pyridine medium. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by high-temperature incineration followed by weighing of residual residue. |
| Heavy Metals | ICP-OES | Quantifies Pb, Cd, Hg, As, and other heavy metals by plasma excitation and elemental emission spectroscopy. |
| Chloride Content | Potentiometric Titration | Measures Cl- concentration using silver nitrate titrant and silver/silver chloride indicator electrode. |
| pH (1% aqueous solution) | pH Meter Measurement | Determines acidity/basicity of a standardized aqueous solution using calibrated glass electrode system. |
| Specific Optical Rotation | Polarimetry | Measures chiral purity by detecting rotation of plane-polarized light in solution at specified concentration and wavelength. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Organic Volatile Impurities (Residual Solvents) | GC-FID | Identifies and quantifies solvents (e.g., methanol, acetone) using gas chromatography with flame ionization detection. |
| Particle Size Distribution | Laser Diffraction | Measures particle size profile in suspension via angular scattering pattern analysis of laser beam. |
| Bulk Density | USP <616> Tap Density Method | Determines mass per unit volume after controlled tapping of a known powder mass in a graduated cylinder. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178°C - 182°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.