Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 90866-33-4 |
| Product name | Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key chiral intermediate for synthesizing statin lipid-lowering drugs (e.g., atorvastatin, rosuvastatin) | Used as a chiral building block to introduce chirality via asymmetric synthesis or enzymatic reduction, enabling construction of the 3,5-dihydroxycarboxylic acid moiety in drug molecules |
| Fine Chemicals | Chiral synthon for preparing other optically active compounds | Participates in organic synthesis reactions—including transesterification, oxidation, reduction, and nucleophilic substitution—while retaining or transforming its chiral center to construct target molecules |
Manufacturing Quality Control of Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | GC-FID or HPLC-UV | Quantitative determination using calibrated chromatographic separation with flame ionization or UV detection |
| Enantiomeric Excess (ee) | Chiral GC or Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase followed by peak area comparison |
| Residual Solvents | GC-FID with headspace sampling | Volatile organic solvents quantified via gas chromatography after thermal equilibration in sealed vials |
| Water Content | Karl Fischer Titration | Electrochemical titration measuring water via iodine-sulfur dioxide reaction in anhydrous methanol-pyridine medium |
| Acid Value | Acid-Base Titration | Neutralization of free carboxylic acid groups with standardized KOH solution using phenolphthalein indicator |
| Chloride Content | Ion Chromatography (IC) | Quantification of chloride ions after sample hydrolysis and separation on an anion-exchange column with conductivity detection |
| Heavy Metals | ICP-OES | Multi-element detection of Pb, Cd, Hg, As, and others after acid digestion and plasma excitation |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard references under controlled lighting |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution at specified concentration and path length |
| Residual Ethanol | GC-FID | Direct quantification of ethanol content using external calibration with flame ionization detection |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities using reversed-phase chromatography with UV detection |
| pH of Aqueous Solution | pH Meter | Potentiometric measurement of hydrogen ion activity in a 1% w/v aqueous solution at 25 C |
Technical Specifications of Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate
| Test Item | Specification |
|---|---|
| Appearance | Colorless to Pale Yellow Liquid |
| Purity | >=98.0% (GC-MS) |
| Optical Rotation | +13.5° to +14.5° (c=1, in CHCl3) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.442 to 1.446 |
| Relative Density (20°C/25°C) | 1.125 to 1.135 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate
Safety Information of Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate
Industrial Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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