(S)-N-ALPHA-T-BUTYLOXYCARBONYL-PYROGLUTAMIC ACID T-BUTYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 91229-91-3 |
| Product name | (S)-N-ALPHA-T-BUTYLOXYCARBONYL-PYROGLUTAMIC ACID T-BUTYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 91229-91-3
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 91229-91-3 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 91229-91-3
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral synthetic intermediates | Used in the synthesis of biologically active drug molecules as key intermediates for constructing chiral centers |
| Organic synthesis | Amino acid derivatives with protecting groups | Applied in peptide and complex molecule synthesis to control reaction selectivity using dual Boc and tert-butyl ester protecting groups |
| Pharmaceutical manufacturing | Prodrug or drug carrier design | Employed in the development of targeted drug delivery systems to enhance drug stability and bioavailability |
Manufacturing Quality Control of 91229-91-3
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm based on peak area comparison against reference standard. |
| Chiral Purity (Enantiomeric Excess) | Chiral HPLC | Measures (S)-enantiomer excess using chiral stationary phase and UV detection, comparing retention times and peak areas of enantiomers. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., THF, toluene, EtOAc) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine-based redox reaction in anhydrous methanol medium. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (Pb, Cd, Hg, As, etc.) after acid digestion by inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-MS | Specific quantification of palladium residues from catalytic hydrogenation steps using ICP-MS after microwave-assisted digestion. |
| Residual Chloride | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or foreign matter under controlled lighting and white background. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Loss on Drying | Gravimetric Heating | Measures weight loss after drying at specified temperature (e.g., 60 C under vacuum) to quantify volatile components and moisture. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light in solution to confirm chiral identity and batch-to-batch consistency. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., diastereomers, hydrolysis products) using gradient HPLC with UV detection. |
Technical Specifications of 91229-91-3
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (by LC-MS) |
| Optical Rotation | -42.0 to -38.0 deg (c=1, in CHCl3) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78.0 to 82.0 °C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 91229-91-3
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 91229-91-3
Packaging of 91229-91-3
Industrial 91229-91-3 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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