China Factory Direct
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| CAS number | 913835-73-1 |
| Product name | 3-BROMO-5-CARBOXYBENZENEBORONIC ACID 97 |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a key intermediate in the synthesis of targeted anticancer agents (e.g., analogues of BTK inhibitors) and boron neutron capture therapy (BNCT) candidates | Applied in Suzuki coupling reactions and palladium-catalyzed cross-coupling |
| Materials Science | Employed as a functionalized building block for constructing covalent organic frameworks (COFs) and metal–organic frameworks (MOFs), imparting fluorescence sensing and gas adsorption capabilities | Applied in solvothermal condensation and interfacial polymerization |
| Organic Synthesis | Used as a versatile boronic acid derivative for preparing polysubstituted aryl compounds and bromoaryl building blocks with protected boronic ester groups | Applied in halogen–boron exchange and selective bromination/carboxyl protection–deprotection sequences |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main compound by UV absorption at specific wavelength using reverse-phase chromatography with external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., starting materials, isomers, de-boronated or brominated by-products) via gradient HPLC separation and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, toluene, methanol) using gas chromatography with flame ionization detection and internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration based on iodine generation and stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pd, Ni, Fe, Cu) using inductively coupled plasma mass spectrometry with isotope dilution or external calibration. |
| Residual Palladium | ICP-OES | Measures palladium from Suzuki coupling catalyst residue using inductively coupled plasma optical emission spectroscopy. |
| Acid Value | Acid-Base Titration | Determines carboxylic acid content by titration with standardized NaOH solution using phenolphthalein indicator or potentiometric endpoint. |
| Boron Content | ICP-OES | Quantifies total boron by measuring boron spectral line intensity after acid digestion and nebulization into plasma. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus under controlled heating rate. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles or discoloration against standard reference under controlled lighting. |
| Loss on Drying | Gravimetric Analysis | Measures volatile loss by weighing sample before and after drying at specified temperature and vacuum/time conditions. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension using angular scattering pattern of laser beam and Mie theory calculation. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 185–189 °C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.