5-Fluoro-2-hydroxybenzonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 91407-41-9 |
| Product name | 5-Fluoro-2-hydroxybenzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Fluoro-2-hydroxybenzonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Fluoro-2-hydroxybenzonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Fluoro-2-hydroxybenzonitrile
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of fungicides such as flutolanil | Flutolanil is prepared via a multi-step process involving nitration, reduction, diazotization, fluorination, and cyanation |
| Pharmaceuticals | Used in the synthesis of fluorinated quinolone antibacterial agents and antitumor candidate compounds | Serves as a starting material for constructing fluorinated benzene ring structures, participating in coupling and cyclization reactions |
| Materials Science | Structural unit in electron-transport materials for organic light-emitting diodes (OLEDs) | Bromination followed by Suzuki or Ullmann coupling to incorporate into conjugated backbones, enabling tuning of energy levels and charge-carrier mobility |
Manufacturing Quality Control of 5-Fluoro-2-hydroxybenzonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 220-254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and detection of impurities using HPLC coupled with diode array detection; identification and quantification based on retention time and spectral match. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppq sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with conductivity detection, calibrated against NaCl standards. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 600-750 C followed by sulfuric acid treatment and final weighing of residual inorganic ash. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition temperature range using calibrated capillary apparatus per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via laser scattering to obtain D10, D50, D90 values according to ISO 13320. |
| Bulk Density | Tap Density Tester | Measurement of mass per unit volume after controlled tapping per USP <616> to assess flow and handling properties. |
| pH of Aqueous Suspension | pH Meter | Determination of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Organic Volatile Impurities (OVI) | GC-MS | Targeted and untargeted screening of volatile and semi-volatile organic impurities using gas chromatography-mass spectrometry with library matching. |
Technical Specifications of 5-Fluoro-2-hydroxybenzonitrile
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 124-128°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Fluoro-2-hydroxybenzonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Fluoro-2-hydroxybenzonitrile
Safety Information of 5-Fluoro-2-hydroxybenzonitrile
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 5-Fluoro-2-hydroxybenzonitrile
Industrial 5-Fluoro-2-hydroxybenzonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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