1-Boc-4-cyanopiperidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 91419-52-2 |
| Product name | 1-Boc-4-cyanopiperidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-Boc-4-cyanopiperidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-Boc-4-cyanopiperidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-Boc-4-cyanopiperidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate (e.g., for synthesis of antidepressants and anticancer agents) | Organic synthesis (Boc protection/deprotection) |
| Agrochemicals | Precursor for insecticide or fungicide synthesis | Catalytic reaction / functional group transformation |
| Materials Science | Preparation of functionalized polymer monomers | Polymerization / modification reaction |
| Research Reagents | Structural modification studies of piperidine derivatives | Laboratory-scale synthesis / chromatographic purification |
Manufacturing Quality Control of 1-Boc-4-cyanopiperidine
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color and physical state (e.g., white to off-white crystals or powder) to determine compliance with standard descriptions. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Utilize a reversed-phase C18 column with a UV detector (e.g., at 210 nm or 220 nm); quantify the main component purity using external standard or area normalization methods. |
| Related Substances/Impurities | HPLC (Gradient Elution) | Optimize mobile phase gradients to separate potential impurities (e.g., de-Boc products, isomers, degradation products); set limits for impurity control. |
| Water Content | Karl Fischer Titration | Determine water content in the sample using potentiometric or volumetric titration methods to ensure compliance with drying loss or moisture specifications (typically ≤0.5%). |
| Residual Solvents | Gas Chromatography (GC) | Employ headspace or direct injection with an FID detector; control residual organic solvents (e.g., methanol, ethyl acetate, dichloromethane) in accordance with ICH Q3C guidelines. |
| Melting Point | Capillary Melting Point Apparatus | Determine the melting temperature range of the sample and compare with standard values (literature value approximately 75–78°C) to assess crystalline purity. |
| Specific Rotation | Polarimeter | For chiral compounds or those with optical activity impurities, measure specific rotation at a defined concentration for stereochemical quality control. |
| Structure Confirmation | Nuclear Magnetic Resonance (NMR), Infrared Spectroscopy (IR), Mass Spectrometry (MS) | Comprehensively use ¹H-NMR and ¹³C-NMR to confirm molecular structure; IR to verify functional groups (e.g., cyano, Boc carbonyl); MS to confirm molecular weight. |
| pH Value (if applicable) | pH Meter (aqueous solution) | Prepare a defined concentration aqueous solution of the sample and measure pH to assess acidity/basicity and potential acidic/basic impurities. |
| Residue on Ignition / Sulfated Ash | Gravimetric Method | Incinerate the sample at high temperature (e.g., 600–800°C) and weigh the residue to control inorganic impurity content (typically ≤0.1%). |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Perform heavy metal testing (e.g., lead, arsenic, cadmium, mercury) according to pharmacopoeial methods to ensure compliance with safety limits (e.g., ≤20 ppm). |
Technical Specifications of 1-Boc-4-cyanopiperidine
| Test Item | Specification |
|---|---|
| Appearance | White to almost white powder or crystals |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 118–122°C |
| Identification (NMR) | Conforms to reference standard |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-Boc-4-cyanopiperidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-Boc-4-cyanopiperidine
Packaging of 1-Boc-4-cyanopiperidine
Industrial 1-Boc-4-cyanopiperidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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