China Factory Direct
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| CAS number | 914225-70-0 |
| Product name | 5'-fluoro-2'-Iodoacetophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Pharmaceutical Intermediates | Used to synthesize fluorinated and iodinated aromatic compounds as precursors for anticancer, antibacterial, or antiviral drugs |
| Agrochemicals | Agrochemical Synthesis Intermediates | Applied as organic synthesis intermediates in the preparation of biologically active agrochemical compounds |
| Organic Synthesis | Synthesis of Aromatic Ketone Derivatives | Served as a key intermediate in modern organic synthesis reactions—including Suzuki coupling and Heck reactions—to construct complex molecular frameworks |
| Materials Science | Synthesis of Functional Materials | Used to prepare aromatic structural units in organic optoelectronic materials or liquid crystal materials |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe sample color and physical state (e.g., white to off-white crystalline powder), checking for foreign particles, caking, or other physical characteristics. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Using a reversed-phase C18 column and UV detector (e.g., 254 nm), determine the main component content by area normalization or external standard method. |
| Related Substances | HPLC (Gradient Elution) | Employ gradient elution to separate potential impurities (e.g., unreacted starting materials, by-products, degradation products); quantitation limit is typically ≤0.1%. |
| Moisture Content | Karl Fischer Titration | Determine water content using potentiometric or volumetric titration; ensure compliance with standards for loss on drying or moisture content (e.g., ≤0.5%). |
| Residual Solvents | Gas Chromatography (GC) | Analyze residual organic solvents (e.g., ethanol, acetone) via headspace or direct injection, using capillary column and FID detection. |
| Melting Point | Capillary Melting Point Apparatus | Determine the melting temperature range and compare with literature values (approximately 75–78°C) to assess purity and crystal form consistency. |
| Structural Confirmation | Nuclear Magnetic Resonance (NMR), Mass Spectrometry (MS) | Use ¹H NMR and ¹³C NMR to confirm hydrogen and carbon framework; ESI-MS or EI-MS to verify molecular weight (M.W. = 262.03 g/mol). |
| Heavy Metals | ICP-MS or Atomic Absorption Spectroscopy | Detect residual elements such as lead, cadmium, mercury, and arsenic; comply with ICH Q3D limits (e.g., total heavy metals ≤20 ppm). |
| Sulfated Ash / Residue on Ignition | Gravimetric Analysis | Weigh residue after high-temperature ignition of sample to evaluate total inorganic impurities (typically required ≤0.1%). |
| Chiral Purity (if applicable) | Chiral HPLC or SFC | If chiral centers are present, use chiral columns to separate enantiomers and ensure optical purity (e.g., ee ≥99%). |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 124.0 - 128.0 °C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.