China Factory Direct
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| CAS number | 914916-98-6 |
| Product name | 6-aMino-5-chloropyriMidine-4-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of antiviral agents (e.g., HCV NS5A inhibitors) | Undergoes amidation with acyl chlorides or acid anhydrides, followed by cyclization, substitution, and other sequential steps to construct the core pyrimidine structure |
| Pesticide R&D | Structural building block for designing novel pyrimidine-based herbicides and fungicides | Introduces nitrogen-containing heterocyclic groups via nucleophilic substitution at the chlorine atom, or forms C–N bonds through metal-catalyzed coupling |
| Organic Synthesis | Multifunctional heterocyclic building block for constructing complex molecular frameworks | Participates in Suzuki or Buchwald–Hartwig coupling under palladium catalysis; or undergoes functional group transformations—such as diazotization–iodination—to prepare derivatives |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, state, and presence of visible impurities under natural light or standard illumination. |
| Purity/Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with an aqueous-organic mobile phase (e.g., methanol or acetonitrile) and a UV detector (typically at 254 nm or 280 nm). Quantify the main component using external or internal standard methods. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Confirm the molecular structure using ¹H-NMR and ¹³C-NMR to verify the position and number of amino, chlorine, and carboxyl groups as per the target structure. |
| Structure Confirmation | Mass Spectrometry (MS) | Obtain molecular ion peaks ([M+H]+ or [M-H]−) via LC-MS or ESI-MS to verify that the molecular weight matches the theoretical value. |
| Water Content | Karl Fischer Titration | Determine trace water content in the sample using Karl Fischer reagent for precise measurement. |
| Residual Solvents | Gas Chromatography (GC) | According to ICH guidelines, detect organic solvents potentially residual from manufacturing processes (e.g., methanol, ethanol, dichloromethane) using an FID detector. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, determine the residual levels of heavy metal elements such as lead, arsenic, cadmium, and mercury to ensure compliance with pharmacopeial or safety standards. |
| Melting Point | Melting Point Apparatus | Measure the initial and final melting temperatures of the compound using an automatic or capillary melting point apparatus for identification and purity assessment. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate the main peak from impurity peaks using gradient elution to detect and quantify process-related impurities and degradation products, evaluating sample stability and purity. |
| pH Value (Solution) | pH Meter Method | Dissolve the sample in water at a specified concentration (e.g., 0.1% w/v) and measure its acidity or alkalinity using a calibrated pH meter. |
| Test Item | Specification |
|---|---|
| Appearance | Off white solid |
| ldentification(NMR) | Conforms to structure |
| Purity | ≥95.0% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.