China Factory Direct
|
|
| CAS number | 914988-10-6 |
| Product name | 3-CYANO-4-OXO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Organic synthesis intermediate | Used to construct piperidine-containing drug molecules; participates in multistep synthetic reactions such as reductive amination and coupling reactions |
| Chemical research | Heterocyclic compound synthesis | Serves as a key intermediate for preparing biologically active nitrogen-containing heterocycles |
| Pharmaceutical manufacturing | Antitumor drug development | Introduced as a structural building block in targeted drug synthesis to incorporate cyano and BOC protecting groups |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities using gradient HPLC-UV; identification and quantification against reference standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents based on retention time and peak area calibration. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generation to determine water content via stoichiometric reaction with Karl Fischer reagent. |
| Heavy Metals | ICP-MS | Multi-element detection of trace metals by inductively coupled plasma mass spectrometry after acid digestion and dilution. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residue by inductively coupled plasma optical emission spectroscopy after microwave digestion. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using a polarimeter at specified temperature and wavelength (e.g., 589 nm, 20 C). |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature range at which solid phase converts to liquid. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity under controlled white light against defined specifications (e.g., white to off-white crystalline powder). |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution by measuring angular variation in intensity of laser light scattered by dispersed particles. |
| Bulk Density | Graduated Cylinder Method | Measurement of mass per unit volume for freely settled powder using standardized cylinder and tapping procedure per USP <616>. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.5% (by GC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.