China Factory Direct
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| CAS number | 915416-45-4 |
| Product name | 3',4',5'-trifluorobiphenyl-2-aMine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of anticancer, antiviral, and central nervous system–targeting drugs | Amine groups are introduced into the target molecular scaffold via aromatic nucleophilic substitution or cross-coupling reactions (e.g., Suzuki, Buchwald–Hartwig) |
| Agrochemicals | Employed as a structural building block for novel, high-efficacy pesticides to enhance molecular affinity toward target enzymes | The trifluorobiphenylamine structure is coupled with heterocyclic or sulfonamide moieties via multistep synthesis to construct the active ingredient |
| Materials Science | Applied in the synthesis of high-performance organic semiconductors or OLED emissive materials | Used as a building block for electron-transport or hole-injection layers, with thin-film devices fabricated via thermal evaporation or solution-processing techniques |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity Determination | High-Performance Liquid Chromatography (HPLC) | Utilizes a reversed-phase chromatography column with a UV detector (e.g., 254 nm) to detect the main peak area; quantification is performed using external standard or area normalization methods. Suitable for separation and quantification of organic impurities and the main component. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Analysis of hydrogen, carbon, and fluorine atomic environments via ¹H NMR, ¹³C NMR, and ¹⁹F NMR to confirm that the molecular structure and substitution positions match the target compound. |
| Molecular Weight Confirmation | Mass Spectrometry (MS), e.g., ESI-MS or HRMS | Electrospray ionization mass spectrometry or high-resolution mass spectrometry measures the molecular ion peak to verify molecular weight and elemental composition, aiding in structural identification. |
| Residual Solvent Detection | Gas Chromatography (GC-FID/HS-GC) | Headspace or direct injection with capillary columns for separation, quantifying residual organic solvents (e.g., methanol, ethyl acetate) using an FID detector. |
| Loss on Drying | Drying Method / Karl Fischer Water Determination | Drying method: Constant weight at 105°C; percentage weight loss is calculated. Karl Fischer method: Titration for precise determination of water content in the sample. |
| Heavy Metal Detection | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | After sample digestion, heavy metal elements such as lead, cadmium, mercury, and arsenic are detected to ensure compliance with pharmacopoeial or ICH Q3D limits. |
| Related Substances (Impurities) Analysis | HPLC with Gradient Elution | Gradient elution enhances separation capability to detect synthetic by-products and degradation products. Qualitative and quantitative analysis is performed based on relative retention times and response factors. |
| Melting Point Determination | Capillary Melting Point Apparatus | A digital melting point instrument measures the initial and final melting temperatures of the compound to assess crystalline purity and batch consistency. |
| Appearance and Color | Visual Inspection / Colorimeter | White to off-white solid is acceptable; colorimeter may be used optionally to quantify L*a*b* values to control batch-to-batch color stability. |
| Specific Rotation (if chiral) | Polarimeter Measurement | If the molecule contains a chiral center, specific rotation must be measured to control enantiomeric purity (this test is typically not applicable as the compound has no chiral center). |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Conforms to reference standard |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.