China Factory Direct
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| CAS number | 916516-89-7 |
| Product name | 2-(4-bromo-2-chlorophenyl)acetic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing anticancer agents (e.g., EGFR inhibitors) | Constructs aryl substituents via palladium-catalyzed cross-coupling reactions (e.g., Suzuki or Heck coupling) |
| Agrochemical Intermediates | Used to prepare active ingredients of novel insecticides and fungicides | Introduces pharmacophores via amidation, esterification, or heterocyclic coupling reactions |
| Organic Synthesis | Multifunctional aryl halogenated carboxylic acid employed for constructing complex molecular frameworks | Participates in organometallic reagent preparation (e.g., Grignard reagents) and transition-metal-catalyzed C–C bond formation reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities by HPLC coupled with diode array detection, using gradient elution and spectral matching. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents based on retention time and peak area calibration. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generation in methanol-based reagent to determine water content stoichiometrically. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion by measuring atomic emission intensities at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation of anions on an ion-exchange column with conductivity detection, calibrated against chloride standards. |
| Bromide Impurity | Ion Chromatography | Same principle as chloride, optimized for bromide retention and detection via suppressed conductivity. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature ashing (700-800 C) to assess inorganic ash content. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using calibrated capillary tube method per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, indicating chiral purity or absence of racemization. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determination of pH in a defined suspension (e.g., 1% w/v in water) using a calibrated glass electrode system. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity vs. angle to derive volume-based particle size distribution in dry or wet dispersion. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (by LC-MS) |
| Melting Point | 124–128°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.