China Factory Direct
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| CAS number | 916792-13-7 |
| Product name | 4-BROMO-2-FLUORO-5-METHYLBENZONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Organic Synthesis | Synthesis of pharmaceutical intermediates | Prepared via bromination, fluorination, and cyanation reactions |
| Pharmaceutical Industry | Intermediates for anticancer or antiviral drugs | Serves as a key intermediate in multistep organic synthesis |
| Pesticide Industry | Intermediates for novel pesticides | Used to construct biologically active aromatic nitrile structures |
| Polymer Materials | Monomers for functional polymer synthesis | Acts as a functional monomer in polymerization reactions |
| Analytical Chemistry | Reference standards or analytical reagents | Employed as reference materials in chromatographic or spectroscopic analysis |
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state (e.g., white to off-white crystalline powder), and presence of foreign matter with the naked eye. |
| Melting Point | Capsule Melting Point Determination | Determine the melting temperature range using a melting point apparatus and compare it to standard values (typically about 90–94 °C) to assess purity. |
| Identification | Infrared Spectroscopy (FT-IR) | Acquire an infrared spectrum of the sample and compare characteristic absorption peaks (e.g., C≡N stretching vibration at ~2230 cm⁻¹, C–F, C–Br, etc.) with reference spectra for consistency. |
| Nuclear Magnetic Resonance Hydrogen Spectrum (¹H NMR) | Determine the hydrogen spectrum in a deuterated solvent to confirm characteristic chemical shifts (e.g., methyl, aromatic protons) and verify structure. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 column and UV detector (e.g., 254 nm), employing external standard or area normalization methods to determine the main component content (typically ≥98.0%). |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use the same conditions as for content determination or a gradient elution program to separate and quantify potential impurities (e.g., starting materials, by-products, degradation products). Typically, individual impurity ≤0.5%, total impurities ≤1.0%. |
| Moisture | Karl Fischer Method | Determine moisture content using volumetric or coulometric titration methods and control within specified limits (e.g., ≤0.5%). |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection with FID detector to determine residual organic solvents from the production process (e.g., toluene, dichloromethane, etc.), meeting ICH Q3C limit requirements. |
| Ignition Residue/ Ash Content | Gravimetric Method | Weigh the remaining inorganic mass after high-temperature calcination to evaluate inorganic impurity content (typically ≤0.1%). |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Digest the sample and measure total heavy metal elements such as lead, cadmium, mercury, and arsenic, complying with pharmacopoeia or client-specific limits (e.g., ≤20 ppm). |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.5% (GC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78-82°C |
| Identification (NMR) | Conforms to reference standard |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.