China Factory Direct
|
|
| CAS number | 916792-15-9 |
| Product name | 4-BROMO-5-FLUORO-2-METHYLBENZONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Serves as a key building block for constructing specific drug molecule scaffolds in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in developing drugs featuring benzenes substituted with cyano, halo, and methyl groups; participates in coupling or nucleophilic substitution reactions. |
| Agrochemicals | Agrochemical Intermediates | Used in synthesizing fluorinated benzyl nitrile-based agrochemicals; bromine and fluorine atoms are introduced to optimize molecular structure, enhancing biological activity and selectivity; incorporated into synthetic processes for insecticides or herbicides. |
| Organic Synthesis | Synthesis of Functional Materials and Fine Chemicals | Leverages its multifunctional character (cyano, bromo, fluoro groups) as a versatile synthon in reactions such as Suzuki coupling and Sandmeyer reactions to construct complex aromatic compounds and precursors for organic optoelectronic materials. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase chromatography with UV detection at 220-254 nm based on peak area comparison to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., isomers, dehalogenated by-products) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents (e.g., toluene, THF, methanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation and stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Measures trace levels of toxic metals (Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Quantifies chloride ions using suppressed conductivity detection after separation on an anion-exchange column. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700-800 C) and subsequent weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against defined standards. |
| Bulk Density | ASTM D1895 Method A | Measures mass per unit volume of freely settled powder using a calibrated cylinder and balance. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of dry powder using Mie scattering theory applied to laser light diffraction patterns. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light by chiral impurities or degradation products using sodium D-line (589 nm) at specified concentration and temperature. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 112–116°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.