1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro- Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 918515-16-9 |
| Product name | 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro- |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro-
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro- Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro-
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Key intermediate for small-molecule kinase inhibitors | Used in the synthesis of BTK (Bruton’s tyrosine kinase) inhibitor candidates, where the core pyrrolopyrimidine scaffold is constructed via multi-step reactions including Suzuki coupling, reductive amination, and cyclization |
| Agrochemical R&D | Structural unit for novel insecticides | Serves as a modification site on heterocyclic agrochemical lead compounds; the chlorine atom participates in nucleophilic substitution to introduce functional side chains, thereby optimizing binding activity toward targets such as the nicotinic acetylcholine receptor |
| Materials Science | Precursor for organic optoelectronic functional materials | Used to prepare conjugated polymers or small-molecule emissive materials; after Vilsmeier–Haack formylation, further condensation builds D–A (donor–acceptor) architectures applied in hole-transport layers of OLED devices |
Manufacturing Quality Control of 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro-
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-MS | Separation and identification of impurities (e.g., starting materials, intermediates, degradants) using gradient HPLC/UPLC with UV or mass spectrometric detection. |
| Residual Solvents | GC-FID or GC-MS | Headspace gas chromatography with flame ionization or mass spectrometric detection to quantify volatile organic solvents (e.g., DMF, THF, methanol) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration based on the stoichiometric reaction of iodine with water in an anhydrous pyridine-methanol medium. |
| Heavy Metals | ICP-MS or ICP-OES | Quantification of elemental impurities (e.g., Pb, Cd, Ni, Pd) after acid digestion, per ICH Q3D, using inductively coupled plasma mass spectrometry or optical emission spectrometry. |
| Chloride Content | Ion Chromatography (IC) or Potentiometric Titration | Anion separation and quantification via IC with conductivity detection, or argentometric titration using silver nitrate and potentiometric endpoint detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating rate (e.g., 1–2 °C/min). |
| Appearance and Color | Visual Inspection / Hazen (APHA) Color Scale | Subjective visual assessment against white background; color intensity quantified by comparison to platinum-cobalt standard solutions. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Measurement of inorganic residue after high-temperature incineration (~700–800 °C) and sulfuric acid treatment, per USP <281>. |
Technical Specifications of 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro-
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 215–219 °C |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro-
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro-
Safety Information of 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro-
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro-
Industrial 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 4-chloro- Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply