China Factory Direct
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| CAS number | 91872-10-5 |
| Product name | 2-AMINO-3,5-DIBROMO-6-METHYLPYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate | Serves as a key structural unit in the synthesis of brominated pyridine-derived pharmaceuticals and candidate drug molecules. |
| Pharmaceutical Industry | Analgesic Drug Development | Used to synthesize novel aminopyridine derivatives as voltage-gated sodium channel blockers for analgesic drug development. |
| Chemical Industry | Organic Synthesis Reagent | Leverages reactivity of its amino and bromo groups in coupling reactions (e.g., Suzuki coupling) or nucleophilic substitution to construct complex heterocyclic compounds. |
| Research Sector | Structure–Activity Relationship (SAR) Studies | Serves as a lead compound or scaffold for functional group modification in structure–activity relationship (SAR) studies of drug molecules. |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state (e.g., white to off-white crystalline powder), and presence of visible impurities. |
| Purity and Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a UV detector (typically around 254 nm). Identify components by retention time and quantify using peak area to determine the main component content. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Utilize ¹H NMR and ¹³C NMR to confirm compound structure, verifying characteristic signals such as amino groups, methyl groups, and bromine substitution positions. |
| Structural Confirmation | Mass Spectrometry (MS) | Determine the molecular ion peak using EI-MS or ESI-MS to verify molecular weight (e.g., m/z ≈ 279/281 [M+H]+, showing double bromine isotope pattern). |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents possibly remaining from manufacturing (e.g., methanol, ethanol, dichloromethane) in accordance with ICH guidelines. |
| Water Content | Karl Fischer Titration | Accurately measure moisture content in the sample; suitable for quality control of active pharmaceutical ingredients sensitive to water. |
| Melting Point | Melting Point Apparatus | Determine melting range using an automated or capillary melting point apparatus to assist in assessing purity and consistency of the substance. |
| Related Substances (Impurities) | HPLC with Gradient Elution | Detect synthesis by-products or degradation products such as unreacted starting materials, debromo impurities, oxidation products, etc., to evaluate impurity profile. |
| Sulfated Ash | Sulfated Ash Residue Method | Weigh the residue after high-temperature incineration of the sample to assess levels of inorganic impurities. |
| Heavy Metals | Sulfide Colorimetry (e.g., Chinese Pharmacopoeia method) or ICP-MS | Detect residual heavy metal elements such as lead, arsenic, and mercury to ensure compliance with pharmacopeial limits. |
| Test Item | Specification |
|---|---|
| Appearance | Brown solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 142–146°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.