ANP 1-28, HUMAN Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 91917-63-4 |
| Product name | ANP 1-28, HUMAN |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for ANP 1-28, HUMAN
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk ANP 1-28, HUMAN Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of ANP 1-28, HUMAN
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | As a diagnostic reagent for assessing hypothalamic-pituitary-adrenal (HPA) axis function and adrenocorticotropic hormone (ACTH) reserve capacity | Key antigen or calibrator in radioimmunoassay (RIA) or immunoradiometric assay (IRMA) |
| Pharmaceutical Industry | For differential diagnosis of adrenal disorders, including Cushing’s syndrome and Addison’s disease | Development of chemiluminescent immunoassay or enzyme-linked immunosorbent assay (ELISA) kits |
| Biopharmaceuticals | As an ACTH analog or fragment for pharmacological research | Solid-phase peptide synthesis and purification |
| Scientific Research | For studying binding characteristics and signal transduction mechanisms of the ACTH receptor (melanocortin 2 receptor, MC2R) | Receptor-ligand binding assays and cellular signaling pathway analysis |
| Drug Development | As a reference standard for quality control and assay of ACTH and related peptide therapeutics | High-performance liquid chromatography (HPLC) and mass spectrometry (MS) analysis |
Manufacturing Quality Control of ANP 1-28, HUMAN
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Identity | Peptide Mapping with LC-MS/MS | Enzymatic digestion followed by liquid chromatography-tandem mass spectrometry to confirm amino acid sequence and disulfide connectivity. |
| Purity | Reversed-Phase HPLC | Separation based on hydrophobicity using a C18 column and UV detection at 214 nm to quantify main peak and related impurities. |
| Assay (Potency) | Amino Acid Analysis (AAA) after acid hydrolysis | Quantification of constituent amino acids via ion-exchange chromatography or UHPLC to determine molar content and calculate peptide concentration. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to measure trace water content in the solid sample. |
| Residual Solvents | Headspace GC-FID | Gas chromatographic separation with flame ionization detection to quantify organic solvents (e.g., acetonitrile, DCM) remaining from synthesis/purification. |
| Heavy Metals | ICP-MS | Inductively coupled plasma mass spectrometry for simultaneous quantification of elemental impurities (e.g., Pb, Cd, Ni, Cu) at sub-pptr levels. |
| Endotoxins | Kinetic Chromogenic LAL Assay | Enzymatic reaction triggered by endotoxin-induced activation of Limulus amebocyte lysate, measured via absorbance change over time. |
| Bioburden | Membrane Filtration with TSA Agar | Microbial enumeration by filtration, membrane transfer to tryptic soy agar, and colony counting after incubation. |
| Disulfide Bridge Integrity | Non-Reducing vs Reducing SDS-PAGE | Electrophoretic mobility shift comparison under non-reducing and reducing conditions to verify correct Cys7-Cys23 pairing. |
| Related Substances | Ion-Exchange HPLC | Separation based on charge differences using a cation-exchange column to detect deamidated, oxidized, or truncated variants. |
| pH (Solution) | Potentiometric pH Measurement | Direct measurement using calibrated glass electrode in a defined aqueous solution of specified concentration and temperature. |
| Appearance | Visual Inspection | Assessment of color, clarity, and physical form (e.g., white to off-white lyophilized powder) against standard reference under controlled lighting. |
Technical Specifications of ANP 1-28, HUMAN
| Test Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.2% |
| Optical Rotation | -15° to -25° (c=1, in 0.1% TFA/water) |
| Solubility | Freely soluble in water and dilute aqueous acetic acid |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of ANP 1-28, HUMAN
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of ANP 1-28, HUMAN
Industrial ANP 1-28, HUMAN Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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