6-Methylcoumarin Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 92-48-8 |
| Product name | 6-Methylcoumarin |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 6-Methylcoumarin
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 6-Methylcoumarin Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 6-Methylcoumarin
| Industry | Application | Process |
|---|---|---|
| Fragrance | Used in formulating vanilla, tobacco, and nut flavorings | Used in fragrance compound synthesis |
| Food Additives | Used as a food flavor enhancer (subject to regulatory limits) | Added during food processing for flavor enhancement |
| Personal Care | Fragrance component in personal care products such as shampoos and body washes | Incorporated into personal care product formulations |
| Tobacco | Used as a modifier in tobacco flavorings to improve smoking quality | Added during tobacco processing |
| Pharmaceutical Intermediates | Raw material for synthesizing anticoagulants or photosensitizers | Employed in chemical synthesis reactions |
| Electroplating | Co-component in electroplating brighteners (for specific formulations) | Formulated into electroplating baths |
Manufacturing Quality Control of 6-Methylcoumarin
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity and Content Determination | High-Performance Liquid Chromatography (HPLC) | Utilizes a C18 column with methanol-water or acetonitrile-water as the mobile phase, detected by UV detector at approximately 320–330 nm. Quantification is performed using external standard or internal standard methods. This method offers high resolution and accuracy and is widely adopted in pharmacopoeial testing. |
| Purity and Content Determination | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Exploits the characteristic absorption peak of 6-methylcoumarin in ethanol or methanol at 320–340 nm. Concentration is determined via standard curve method. The procedure is simple and suitable for rapid screening, but susceptible to interference from impurities. |
| Melting Point Determination | Capillary Melting Point Apparatus Method | Sample is packed into a capillary tube and heated gradually; the melting range (literature value ~85–88°C) is observed. Used for preliminary purity assessment—impurities typically cause a lowered melting point or broader melting range. |
| Moisture Determination | Karl Fischer Titration | Quantitatively determines trace moisture through reaction between iodine, sulfur dioxide, and pyridine. Suitable for moisture-sensitive active pharmaceutical ingredients, offering high precision (down to ppm level). |
| Impurity Analysis | Thin-Layer Chromatography (TLC) | Uses silica gel plates with ethyl acetate-petroleum ether (e.g., 1:1) as the developing solvent. Spots are visualized under UV light (254/365 nm), and compared with reference standards for qualitative detection of major impurities or degradation products. |
| Impurity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | Applicable for volatile impurities or residual solvents. After derivatization if necessary, samples are injected and unknown impurities identified based on mass spectral fragmentation patterns. High sensitivity enables trace-level impurity screening. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (¹H-NMR, ¹³C-NMR) | Measured in DMSO-d₆ or CDCl₃. Characteristic proton signals (e.g., C6-CH₃ at δ ~2.3 ppm, aromatic protons at δ ~6.8–7.8 ppm) and carbon signals confirm molecular structure. Considered the gold standard for structural elucidation. |
| Structural Confirmation | Fourier Transform Infrared Spectroscopy (FT-IR) | Identifies characteristic functional group absorptions (e.g., C=O stretch ~1700 cm⁻¹, C-O-C ~1200 cm⁻¹) to verify the coumarin scaffold and detect possible functional group changes or contamination. |
| Particle Size and Polymorphic Analysis | X-Ray Diffraction (XRD) | Used to analyze the crystalline structure and polymorphism (e.g., presence of multiple forms) of 6-methylcoumarin, ensuring consistency in physical properties during formulation development—particularly critical in active pharmaceutical ingredient development. |
| Solvent Residue Testing | Gas Chromatography with Flame Ionization Detection (GC-FID) | Follows ICH Q3C guidelines to determine residual organic solvents (e.g., methanol, ethanol, ethyl acetate) from manufacturing processes. Quantified using external standard method with FID detection, ensuring compliance with pharmacopeial limits. |
Technical Specifications of 6-Methylcoumarin
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 142–146°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 6-Methylcoumarin
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 6-Methylcoumarin
Packaging of 6-Methylcoumarin
Industrial 6-Methylcoumarin Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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