4,4'-Biphenol Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 92-88-6 |
| Product name | 4,4'-Biphenol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty GradeElectronic GradeMaterial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4,4'-Biphenol
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4,4'-Biphenol Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4,4'-Biphenol
| Industry | Application | Process |
|---|---|---|
| Polymers | Monomer for synthesizing polyaryletherketones (e.g., polyetheretherketone, PEEK) | Condensation polymerization |
| Pharmaceuticals | Intermediate for synthesizing biologically active compounds | Organic synthesis, substitution reactions |
| Dyes | Intermediate for preparing azo dyes and functional dyes | Diazotization and coupling reactions |
| Electronic Materials | Used to prepare liquid crystal monomers or high-heat-resistance polymers | Polymerization or functional group modification |
| Agrochemicals | Intermediate for synthesizing certain fungicides or plant growth regulators | Multistep organic synthesis |
Manufacturing Quality Control of 4,4'-Biphenol
| Milestone Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Utilizes a C18 reversed-phase column with methanol-water or acetonitrile-water as the mobile phase, detected by UV detector (wavelength 254 nm or 280 nm). Quantification is performed using external standard or internal standard method, enabling effective separation of impurities and accurate determination of purity. |
| Impurity Profile (Organic Impurities) | HPLC-UV / HPLC-MS | Gradient elution HPLC is used to separate potential impurities such as mono-hydroxybiphenyl, halogenated compounds, and oxidation products. Qualitative and quantitative analysis is achieved via UV detection or mass spectrometry (MS), meeting ICH Q3B impurity control requirements. |
| Melting Point | Melting Point Determination (by Melting Point Apparatus) | Determined according to Chinese Pharmacopoeia or USP methods using capillary tube or automated melting point instrument. The melting range (literature value ~145–148°C) serves as an initial assessment of purity and crystalline form consistency. |
| Moisture Content | Karl Fischer Titration (KF) | Based on the stoichiometric reaction between Karl Fischer reagent and water, moisture content is determined by coulometric or volumetric titration. Ensures compliance with formulation process requirements for moisture control (typically ≤0.5%). |
| Ash Content (Inorganic Impurities) | Residue on Ignition (Charring Residue Method) | Sample is ashed at high temperature (500–600°C), and the residual inorganic matter is weighed to assess metal salts or inorganic impurities. Meets pharmacopeial standards for control of inorganic impurities in organic substances. |
| Solvent Residues | Gas Chromatography (GC) | Headspace or direct injection GC-FID is used to detect residual organic solvents from manufacturing processes (e.g., methanol, ethanol, acetone, DMF). Controlled according to ICH Q3C guidelines. |
| Particle Size Distribution (if applicable) | Laser Particle Size Analysis | For powder forms or materials intended for formulation, laser diffraction is used to determine particle size distribution, ensuring adequate solubility and blend uniformity in downstream processing. |
| Inorganic Anions (e.g., Chloride, Sulfate) | Ion Chromatography (IC) or Colorimetric Methods | Ion chromatography is employed for separation and quantification of anions such as chloride and sulfate, or classical colorimetric methods (e.g., silver nitrate titration for chloride) are used to ensure compliance with pharmaceutical-grade limits for inorganic impurities. |
| Polymorphic Identification | X-Ray Powder Diffraction (XRPD) | Characteristic diffraction peaks are used to identify crystalline forms, ensuring consistent polymorphism and preventing variations that may affect solubility and stability—particularly critical in drug development. |
| UV-Visible Absorption Spectra | UV-Vis Spectrophotometry | Sample is dissolved in ethanol or methanol, and absorption spectra are measured across 200–400 nm. A characteristic absorption peak (λmax ≈ 275 nm) is used for identification and concentration estimation (requires correction with HPLC data). |
Technical Specifications of 4,4'-Biphenol
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow crystalline powder |
| Purity | >=99.0% (by LC-MS) |
| Melting Point | 248–252°C |
| Total Impurities | <=1.0% |
| Single Impurity | <=0.3% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4,4'-Biphenol
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4,4'-Biphenol
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Industrial 4,4'-Biphenol Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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