ISOPROPYL METHANESULFONATE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 926-06-7 |
| Product name | ISOPROPYL METHANESULFONATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeIndustrial GradeElectronic GradeReagent GradeCosmetic GradeFood Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for ISOPROPYL METHANESULFONATE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk ISOPROPYL METHANESULFONATE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of ISOPROPYL METHANESULFONATE
| Industry | Application | Process |
|---|---|---|
| Pesticides | Manufacture of herbicides and insecticides | Used as an intermediate or solvent |
| Pharmaceuticals | Drug synthesis | Used as a sulfonation reagent |
| Cosmetics | Cosmetic formulation | Used as a solvent |
| Electronics | Electronic materials manufacturing | Used as a cleaning agent or solvent |
| Materials Science | Polymer production | Used as a crosslinking agent or initiator |
| Agriculture | Plant growth regulator manufacturing | Used as an intermediate |
| Dyes | Dye and pigment manufacturing | Used as a solvent or reactant |
| Laboratory | Chemical synthesis | Used as a reagent |
Manufacturing Quality Control of ISOPROPYL METHANESULFONATE
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Assay | Gas Chromatography (GC) | Uses a capillary column (e.g., DB-5 or HP-INNOWAX) and FID detector to measure the peak area of isopropyl mesylate. Quantification is performed using internal standard method (e.g., n-hexane or toluene) or external standard method, suitable for assay analysis of high-purity raw materials. |
| Impurity Testing (Organic Impurities) | Gas Chromatography-Mass Spectrometry (GC-MS) | Couples mass spectrometric detection with GC to identify and quantify potential organic impurities such as isopropanol, methanesulfonic acid, and unreacted starting materials. Offers high sensitivity and structural confirmation capability. |
| Water Content | Karl Fischer Titration | Employs coulometric or volumetric Karl Fischer reagents to accurately determine trace moisture levels in the sample, ensuring compliance with specified limits (typically ≤0.1%) to prevent hydrolysis into methanesulfonic acid and isopropanol. |
| Residual Solvents (e.g., Isopropanol) | Headspace-Gas Chromatography (HS-GC) | Utilizes headspace sampling to avoid interference from direct injection, followed by GC-FID detection of residual volatile solvents such as isopropanol. Complies with ICH Q3C guidelines. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, heavy metal content (e.g., lead, cadmium, arsenic, mercury) is determined by AAS or ICP-MS to ensure compliance with pharmacopeial requirements (e.g., USP/EP) for genotoxic impurity control in raw materials. |
| Acidity/Alkalinity | pH Meter or Acid-Base Titration | The sample is dissolved in a suitable solvent (e.g., ethanol or water), and pH is measured using a pH meter or determined via titration with standard alkali solution. Controls acidity due to potential hydrolysis of mesylate esters, ensuring pH remains within a safe range (e.g., pH 4–7). |
| Melting Point/Boiling Point | Melting Point Apparatus or Boiling Point Analyzer | Used as physical constants for identity confirmation and purity assessment. Isopropyl mesylate has a melting point of approximately -20°C and a boiling point of about 135–138°C, aiding in preliminary identification. |
| Genotoxic Impurity Control | LC-MS/MS (Liquid Chromatography-Tandem Mass Spectrometry) | High-sensitivity monitoring of trace-level mesylate ester impurities (e.g., methyl mesylate, ethyl mesylate) using ESI negative ion mode. Detection limits can reach ppb levels, meeting ICH M7 requirements for control of potential mutagenic impurities. |
| Appearance and Color | Visual Inspection or Colorimetric Method | Sample should be a colorless to slightly yellow transparent liquid, free from visible particles. Color may be quantitatively controlled when necessary using a colorimeter (e.g., APHA color scale). |
Technical Specifications of ISOPROPYL METHANESULFONATE
| Test Item | Specification |
|---|---|
| Appearance | Colorless to light yellow clear liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.425–1.435 |
| Relative Density (20°C/25°C) | 1.10–1.14 g/cm³ |
| Odor | Characteristic ester-like odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of ISOPROPYL METHANESULFONATE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of ISOPROPYL METHANESULFONATE
Packaging of ISOPROPYL METHANESULFONATE
Industrial ISOPROPYL METHANESULFONATE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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