China Factory Direct
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| CAS number | 928664-98-6 |
| Product name | 4-ISOXAZOLEBORONIC ACID PINACOL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Boronic ester building block for Suzuki-Miyaura cross-coupling to synthesize active pharmaceutical ingredients (APIs) containing isoxazole rings, including intermediates for anticancer, anti-inflammatory, and central nervous system drugs | Cross-coupling with aryl/heteroaryl halides under palladium catalysis (e.g., Pd(dppf)Cl₂), typically conducted at 80–100 °C in basic conditions (e.g., K₂CO₃, Cs₂CO₃) and inert solvents (e.g., 1,4-dioxane, DMF) |
| Pesticide R&D | Construction of bioactive isoxazole-based agrochemical scaffolds, such as fungicidal and insecticidal candidate molecules | Participation in metal-catalyzed C–C bond formation to introduce substituted isoxazole moieties onto heterocyclic or aromatic cores, thereby optimizing physicochemical properties and target-binding activity |
| Materials Science | Functional monomer for electron-transport layers in organic light-emitting diodes (OLEDs) and conjugated polymers, enhancing carrier mobility and thermal stability of devices | Suzuki coupling to incorporate isoxazole boronic ester units into conjugated backbones (e.g., fluorene or carbazole derivatives), enabling precise energy-level tuning and thin-film morphology optimization |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase chromatography with UV detection at 210-230 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Separates and quantifies impurities (e.g., residual starting materials, de-boronated by-products, isomers) using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents (e.g., THF, toluene, ethyl acetate) by gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation in pyridine-free reagents; based on stoichiometric reaction of water with iodine and sulfur dioxide. |
| Heavy Metals | ICP-OES | Measures total content of regulated metals (e.g., Pb, Cd, Ni, Fe) after acid digestion by optical emission spectroscopy detecting element-specific atomic emission lines. |
| Residual Boron | ICP-OES | Quantifies total boron content post-digestion using characteristic boron emission line (249.773 nm) to confirm complete esterification and absence of free boric acid. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and presence of impurities affecting lattice integrity. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of bulk sample against established reference (white to off-white crystalline powder, free from visible particulates or discoloration). |
| Test Item | Specification |
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| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.