2-Benzyloxy-pyridine-5-boronic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 929250-35-1 |
| Product name | 2-Benzyloxy-pyridine-5-boronic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Benzyloxy-pyridine-5-boronic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Benzyloxy-pyridine-5-boronic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Benzyloxy-pyridine-5-boronic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a key intermediate in the synthesis of selective JAK1 inhibitors (e.g., upadacitinib) | Applied in Suzuki-Miyaura cross-coupling reactions |
| Pharmaceuticals | Used to construct the molecular scaffold of targeted anticancer drugs containing pyridyl groups | Applied in palladium-catalyzed coupling reactions between boronic acids and aryl halides |
| Agrochemicals | Serves as a heterocyclic functional group precursor in novel insecticidal or fungicidal molecules | Applied in transition metal-catalyzed C–C bond formation reactions |
| Materials Science | Used in the synthesis of photoelectrically active organic conjugated polymers | Applied in Suzuki coupling polymerization reactions |
Manufacturing Quality Control of 2-Benzyloxy-pyridine-5-boronic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time relative to reference standards. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common organic solvents (e.g., methanol, ethyl acetate, toluene) based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to determine water content via stoichiometric reaction with Karl Fischer reagent. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, Ni) after acid digestion, using inductively coupled plasma mass spectrometry for ultra-trace sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against chloride standard calibration curve. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C followed by weighing of residual inorganic ash after treatment with sulfuric acid. |
| Particle Size Distribution | Laser Diffraction | Measurement of scattered laser light intensity as a function of angle to calculate particle size distribution in a dispersed slurry. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, observed visually in a calibrated capillary tube under controlled heating rate. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution to assess chiral purity and identity. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determination of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using a calibrated glass electrode pH meter. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residue after microwave-assisted acid digestion using inductively coupled plasma optical emission spectroscopy. |
Technical Specifications of 2-Benzyloxy-pyridine-5-boronic acid
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Benzyloxy-pyridine-5-boronic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Benzyloxy-pyridine-5-boronic acid
Safety Information of 2-Benzyloxy-pyridine-5-boronic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Benzyloxy-pyridine-5-boronic acid
Industrial 2-Benzyloxy-pyridine-5-boronic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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