China Factory Direct
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| CAS number | 93-35-6 |
| Product name | 7-Hydroxycoumarin |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Applications | Process |
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| Pharmaceuticals | Anticoagulant drug intermediate; fluorescent probe for bioimaging | Used as a key intermediate in the synthesis of coumarin-based anticoagulants such as warfarin; forms fluorescent labels via condensation of its hydroxyl group with aldehyde groups in cell staining |
| Personal Care & Cosmetics | Sunscreen agent; fluorescent whitening agent | Incorporated into sunscreen formulations to absorb UV-B radiation; reacted with dichlorotriazine to produce fluorescent whitening agent CBS-X for detergent applications |
| Analytical Chemistry | Fluorescent indicator; metal ion detection reagent | Forms highly fluorescent complexes with Al³⁺, Fe³⁺, and other metal ions in pH 7–10 buffered systems, enabling spectrophotometric detection |
| Pesticides | Insecticide intermediate | Applied in the benzopyran ring construction step during synthesis of coumarin-based rodenticides (e.g., bromadiolone) |
| Materials Science | Hole-transport layer dopant for organic light-emitting diodes (OLEDs) | Codetected with TPD via vacuum thermal evaporation to enhance hole mobility and electroluminescent efficiency |
| Test Item | Common Testing Methods | Method Overview |
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| Assay | High-Performance Liquid Chromatography (HPLC) | Uses a C18 reversed-phase column and a UV detector (e.g., λ=320 nm). Quantification is performed using external or internal standard methods. Offers high sensitivity and good reproducibility; commonly used in pharmacopoeial methods. |
| Purity Analysis | HPLC or Thin-Layer Chromatography (TLC) | HPLC separates and quantifies impurities; TLC is used for rapid screening of impurity spots, with visualization under UV light or using chromogenic reagents to assess purity. |
| Structural Confirmation | Ultraviolet-Visible Spectrophotometry (UV-Vis), Infrared Spectroscopy (IR), Nuclear Magnetic Resonance (NMR), Mass Spectrometry (MS) | UV identifies characteristic absorption peaks (~320 nm); IR detects functional groups; NMR and MS provide precise molecular structural information, often used for comparison with reference standards. |
| Melting Point Determination | Capillary Melting Point Apparatus | Determines the temperature at which a substance transitions from solid to liquid (melting point of 7-hydroxycoumarin is approximately 205–208°C), used for preliminary identification and purity assessment. |
| Loss on Drying | Oven Drying Method (constant weight at 105°C) | Sample is weighed and dried at a specified temperature until constant weight. The percentage weight loss is calculated to control moisture and volatile content. |
| Sulfated Ash / Residue on Ignition | High-Temperature Ashing (600–800°C) | Sample is incinerated at high temperature and the remaining inorganic residue is weighed to evaluate inorganic impurities or residual metal catalysts. |
| Heavy Metals Test | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) | Detects harmful elemental impurities such as lead, arsenic, mercury, and cadmium, ensuring compliance with pharmacopoeial or ICH Q3D limits. |
| Related Substances / Impurity Profiling | HPLC (Gradient Elution) | Gradient elution is employed to separate the main component from potential process-related impurities or degradation products. Impurity levels are calculated using area normalization or self-reference methods. |
| Solubility Testing | Visual Inspection or Turbidimeter Method | Observe dissolution behavior in specified solvents (e.g., water, ethanol, DMSO); serves as a basic physicochemical evaluation prior to formulation development. |
| pH Value (if in solution) | pH Meter Measurement | If prepared as a solution, pH is measured to assess stability or its impact on formulation (7-hydroxycoumarin exhibits weak acidity). |
| Test Item | Specification |
|---|---|
| Appearance | Light orange powder |
| Purity | ≥98.0% |
| Water | ≤1.0% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.