China Factory Direct
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| CAS number | 931-40-8 |
| Product name | 4-HYDROXYMETHYL-1,3-DIOXOLAN-2-ONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Organic Synthesis | Used as a hydroxymethylation reagent and as an intermediate for cyclic acetal protecting groups | Reacts with aldehydes and ketones under basic conditions to introduce a hydroxymethyl group and form a stable five-membered cyclic acetal; commonly applied in carbohydrate chemistry and natural product synthesis for selective protection of vicinal diols or carbonyl groups |
| Pharmaceutical Intermediates | Used in the synthesis of antiviral agents (e.g., acyclovir derivatives) and nucleoside prodrugs | Undergoes ring-opening, substitution, and phosphorylation steps to construct nucleoside analog scaffolds bearing C-hydroxymethyl modification |
| Polymer Chemistry | Acts as a functional monomer in copolymerization to impart hydrophilicity and degradability to polymers | Copolymerized with epichlorohydrin, formaldehyde, and other monomers to produce water-sensitive resins containing acetal linkages, suitable for controlled-release materials or temporary adhesives |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantifies main component peak area relative to calibration curve using volatile organic compound separation and flame ionization detection. |
| Water Content | Karl Fischer Titration | Measures water via stoichiometric reaction between water, iodine, sulfur dioxide, and base in methanol medium. |
| Acidity (as HCl) | Acid-Base Titration with NaOH | Determines acidic impurities by titration with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing and subsequent weighing. |
| Heavy Metals | ICP-OES | Quantifies trace metal contaminants (e.g., Pb, Cd, Fe) based on element-specific atomic emission intensities. |
| Chloride Content | Ion Chromatography (IC) | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particulates or phase separation under controlled lighting. |
| Melting Point | Capillary Melting Point Determination | Measures temperature range at which solid transitions to liquid using calibrated capillary apparatus. |
| Specific Optical Rotation | Polarimetry | Determines chiral purity by measuring angle of rotation of plane-polarized light through a solution. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Detects and quantifies volatile organic solvents by analyzing vapor phase above sample at equilibrium temperature. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of solid particles in suspension based on angular scattering pattern of laser beam. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines hydrogen ion activity using calibrated glass electrode and reference electrode in aqueous slurry or saturated solution. |
| Test Item | Specification |
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| Appearance | Light yellow liquid |
| Purity(GC) | min. 90.0 % |
| NMR | Conforms to structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.