5-Azacytosine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 931-86-2 |
| Product name | 5-Azacytosine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Azacytosine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Azacytosine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Azacytosine
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Synthetic intermediate for anticancer drugs | Used as a nucleoside analog in the synthesis of anticancer agents, such as azacitidine |
| Pharmaceuticals | Reagent for epigenetic research | Applied in studies of DNA methylation inhibition and gene expression regulation mechanisms |
| Biochemistry | Nucleic acid research | Used to synthesize modified RNA/DNA probes for investigating the impact of base modifications on nucleic acid structure and function |
| Agriculture | Pesticide development | Employed as a structural building block in the development of novel agrochemicals or plant growth regulators |
| Materials Science | Functional material synthesis | Utilized as an organic synthetic intermediate to construct heterocyclic compounds or polymeric structures with specific functionalities |
| Environmental Science | Reference standard for environmental contaminant analysis | Applied in detection and quantitative analysis of structurally related compounds in environmental samples |
| Education & Research | Teaching and research reagent | Used in organic synthesis, medicinal chemistry, and biochemistry laboratory instruction and research at universities and research institutions |
Manufacturing Quality Control of 5-Azacytosine
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Reverse-phase high-performance liquid chromatography (RP-HPLC) is used, with a C18 column as the stationary phase. The mobile phase is usually methanol-phosphate buffer (e.g., phosphate buffer at pH 7.0), and the detection wavelength is 260–270 nm. This method can accurately determine the content of 5-azacytidine, offering high sensitivity and repeatability, and is currently the most commonly used quantitative method. |
| Purity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | It is suitable for the analysis of volatile impurities or derivatized 5-azacytidine derivatives. After derivatization (e.g., acetylation), it can be analyzed by GC-MS for qualitative and semi-quantitative analysis of trace impurities and structural confirmation. |
| Impurity Testing | High-Performance Liquid Chromatography (HPLC) - UV/ELSD | HPLC combined with ultraviolet detector (UV) or evaporative light scattering detector (ELSD) can separate and detect related substances other than the main component (e.g., synthetic intermediates, degradation products). It is commonly used to evaluate the limit of process impurities and degradation products. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H NMR and ¹³C NMR provide detailed information about the molecular structure, used to confirm the chemical structure, substitution position, and stereochemistry of 5-azacytidine, and is a key technique for structural confirmation. |
| Molecular Weight Determination | LC-MS (Liquid Chromatography-Mass Spectrometry) | It is used to accurately determine the molecular weight, confirming whether the target compound matches the expected molecular formula ([M+H]⁺ ion peak), and can also help identify impurities and metabolites, which is crucial for quality control and structural verification. |
| Residual Solvent Testing | Gas Chromatography (GC) | Using headspace injection or direct injection, with capillary columns (e.g., DB-624, HP-5) and a flame ionization detector (FID), it is used to detect residual organic solvents (e.g., ethanol, acetone, dichloromethane) from the production process, complying with ICH Q3A/B standards. |
| Water Content | Karl Fischer Titration | Specifically used to determine the water content in samples, with high accuracy and sensitivity, suitable for moisture-sensitive drug raw materials, ensuring product stability and storage conditions meet requirements. |
| Melting Point Determination | Micro Melting Point Apparatus Method | By observing the melting behavior of the sample during heating, the melting point range is determined. It can be used to preliminarily assess purity and distinguish authenticity, but it is an auxiliary method and should be combined with other methods for comprehensive judgment. |
Technical Specifications of 5-Azacytosine
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 210–215°C |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Azacytosine
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| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Azacytosine
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Industrial 5-Azacytosine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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