China Factory Direct
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| CAS number | 93107-30-3 |
| Product name | 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the antibacterial drug ciprofloxacin | Prepared as the active pharmaceutical ingredient (API) for ciprofloxacin via multi-step organic synthesis, including fluorination, cyclization, and carboxylation |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of visible foreign particles under natural light or standard illumination. |
| Identification | Infrared Spectroscopy (IR) | Compare the sample spectrum with a reference standard to confirm consistency in functional groups and molecular structure. |
| High-Performance Liquid Chromatography (HPLC) | Identify by comparing retention times with those of reference standards to ensure consistency of target peaks. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase columns (e.g., C18) and UV detection (around 278 nm), quantifying the main component via external or internal standard methods. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate impurities using gradient or isocratic elution; detect and quantify degradation products or synthetic by-products. Total impurities typically required to be ≤0.5%. |
| Moisture Content | Karl Fischer Titration | Accurately determine moisture content using titration, suitable for trace moisture analysis. |
| Loss on Drying (LOD) | Thermogravimetric Analysis (LOD) | Dry the sample at a specified temperature (e.g., 105°C) until constant weight, calculating the percentage of weight loss to reflect volatile components. |
| Residue on Ignition (Ash Content) | Sulfated Ash Method | After high-temperature incineration, treat residue with sulfuric acid to determine non-volatile inorganic impurities. |
| Heavy Metals | Sulfide Colorimetry or Atomic Absorption Spectroscopy (AAS) | Determine total levels of heavy metals such as lead, cadmium, and mercury via colorimetric reactions or instrumental analysis. Typically limited to ≤20 ppm. |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents (e.g., methanol, ethanol, dichloromethane, DMF) potentially remaining from synthesis, complying with ICH Q3C guidelines. |
| Polymorphic Analysis | X-Ray Powder Diffraction (XRD) | Analyze crystal structure to ensure polymorphic consistency, especially critical for quality control of polymorphic drugs. |
| Particle Size Distribution | Laser Particle Size Analysis | Determine particle size and distribution, which affect dissolution behavior and bioavailability; commonly used for raw material control prior to formulation. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 248–252°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.