China Factory Direct
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| CAS number | 93267-04-0 |
| Product name | BOC-BETA-IODO-ALA-OME |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral building block for synthesizing drug molecules or intermediates containing iodinated alanine structures | Introduced into target molecules via deprotection, coupling, or substitution reactions; commonly applied in stereoselective synthesis of peptides or small-molecule drugs |
| Organic Synthesis | Chiral auxiliary or building block for asymmetric synthesis | Leverages its chiral center and iodine atom reactivity in cross-coupling reactions (e.g., Suzuki, Heck) or nucleophilic substitution reactions |
| Biochemical Research | Synthesis of peptides containing non-natural amino acids for protein function studies or probe development | Incorporated as an iodinated non-natural amino acid monomer into peptide chains during solid-phase or liquid-phase peptide synthesis (SPPS/LPPS) |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Enantiomeric Purity (ee%) | Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase, with quantification based on peak area ratio. |
| Residual Solvents (e.g., MeOH, DCM, THF) | GC-FID | Headspace GC with flame ionization detection, calibrated against USP/ICH Q3C-compliant solvent standards. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with Karl Fischer reagent. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification after acid digestion, using isotopic dilution or external calibration for trace metal impurities per ICH Q3D. |
| Inorganic Chloride (as Cl⁻) | Ion Chromatography (IC) | Separation and conductivity detection of chloride anions in aqueous extract; quantified against NaCl calibration standards. |
| Residual Palladium (if Pd-catalyzed synthesis used) | ICP-OES | Quantitative analysis after microwave-assisted nitric/hydrochloric acid digestion, per ICH Q3D Class 1 element limits. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective assessment against water-white reference; color measured spectrophotometrically per APHA (Pt-Co) scale. |
| Melting Point | Digital Melting Point Apparatus | Thermal transition detection via controlled heating and optical observation of solid-to-liquid phase change. |
| Specific Optical Rotation | [α]D | Measurement of plane-polarized light rotation in solution at 589 nm (Na D-line), reported as degrees per g/mL/dm to confirm chiral integrity. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Optical Rotation | -5.0 to -3.0 deg (c=1, CHCl3) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 58.0 to 62.0 °C |
| Identification (NMR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.