8-BROMO-6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 933190-51-3 |
| Product name | 8-BROMO-6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 8-BROMO-6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 8-BROMO-6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 8-BROMO-6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key intermediate in the development of pyrimidine-based and kinase inhibitor drugs | Serves as a core scaffold or building block for constructing drug molecules via Suzuki coupling, Buchwald–Hartwig amination, and related reactions |
| Pharmaceutical Chemicals | Synthesis of CDK (cyclin-dependent kinase) inhibitors | Used to synthesize imidazopyridazine-based candidate drug compounds, enabling pharmacophore optimization |
| Organic Synthesis | Custom synthesis of imidazopyridazine derivatives | Leverages differential reactivity of halogen atoms (bromine, chlorine) to enable sequential nucleophilic substitution or metal-catalyzed cross-coupling reactions |
| Biochemistry | Structural modification of bioactive molecules and structure–activity relationship (SAR) studies | Enables screening of novel compounds with targeted biological activity through chemical modification at the C-8 and C-6 positions |
Manufacturing Quality Control of 8-BROMO-6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., regioisomers, dehalogenated by-products) via gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures trace organic solvents (e.g., DMF, THF, methanol) using gas chromatography with flame ionization detection and internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration using iodine generation in pyridine-free reagent, based on stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Pd) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Bromide Content | Ion Chromatography | Separates and quantifies bromide ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after controlled ashing at 600 C and weighing of the cooled crucible. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus under controlled heating rate. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particles or discoloration against white/black background under controlled lighting. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of solid particles in suspension using Mie scattering theory and optical detection of diffracted laser light. |
| Bulk Density | Tap Density Measurement | Determines mass per unit volume after standardized tapping of a graduated cylinder containing the sample. |
Technical Specifications of 8-BROMO-6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE
| Test Item | Specification |
|---|---|
| Appearance | Brown solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 8-BROMO-6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 8-BROMO-6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE
Safety Information of 8-BROMO-6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 8-BROMO-6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE
Industrial 8-BROMO-6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply