China Factory Direct
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| CAS number | 935534-47-7 |
| Product name | 5-bromo-4-(trifluoromethyl)pyrimidin-2-amine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key Intermediate | Serves as a building block for synthesizing pyrimidine-containing active pharmaceutical ingredients (APIs); the amino and bromo substituents enable coupling reactions (e.g., Suzuki coupling) or nucleophilic substitution to develop kinase inhibitors and other novel therapeutics. |
| Agrochemicals | Core Intermediate | Used in synthesizing novel fluorinated agrochemicals (e.g., fungicides or insecticides); the trifluoromethyl group imparts lipophilicity and metabolic stability, enhancing efficacy and environmental adaptability. |
| Organic Synthesis | Fluorinated Building Block | Applied in C–N or C–C bond-forming reactions to construct complex fluorinated heterocyclic compounds; widely used for structural modification and derivatization of functional materials and biologically active molecules. |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification via reverse-phase HPLC with UV detection at 254 nm using external standard calibration. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV against reference standards or area normalization. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine reagent to determine trace water based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature using controlled heating and optical observation. |
| Bulk Density | USP <616> Method I | Measurement of mass per unit volume for freely settled powder using standardized cylinder and balance. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution based on angular dependence of scattered laser light intensity. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light through a solution in a defined pathlength cell. |
| pH of Aqueous Suspension | pH Meter | Determination of hydrogen ion activity in a saturated aqueous suspension using calibrated glass electrode. |
| Test Item | Specification |
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| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Conforms to reference standard |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.