China Factory Direct
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| CAS number | 93760-41-9 |
| Product name | L-Ser(Bzl)-OtBu.HCl |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Serine protecting reagent in peptide synthesis | Used in solid-phase or solution-phase peptide synthesis to selectively protect the serine side-chain hydroxyl group (O-benzyl) and the α-amino group (tert-butoxycarbonyl, as hydrochloride salt), facilitating subsequent deprotection and coupling reactions; the O-benzyl group is acid-stable and removable by hydrogenolysis, while the Boc group is base-stable and cleavable under mild acidic conditions (e.g., TFA) |
| Organic Synthesis | Chiral intermediate construction | Employed as a chiral building block bearing two orthogonal protecting groups in asymmetric synthesis, cyclization reactions, or enzymatic transformations to construct side-chain architectures of complex molecules such as β-lactam antibiotics and protease inhibitors |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by retention time and UV absorbance relative to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DCM, MeOH, EtOAc) via flame ionization detection after headspace or direct injection. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration with iodine-based reagent in pyridine-free medium. |
| Chloride Content | Ion Chromatography (IC) | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Heavy Metals | ICP-MS | Detects trace metal contaminants (e.g., Pb, Cd, Ni) by mass spectrometric analysis of plasma-ionized sample. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation at 589 nm to confirm chiral integrity and enantiomeric purity. |
| Residual Palladium | ICP-MS | Quantifies residual Pd catalyst from synthesis using high-sensitivity mass spectrometry. |
| Loss on Drying (LOD) | Gravimetric Analysis | Determines volatile content by weight loss after controlled heating under specified temperature and vacuum conditions. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a defined aqueous suspension using calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension by angular scattering intensity of laser beam. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms via filtration, membrane transfer to culture media, and colony enumeration. |
| Test Item | Specification |
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| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -15.0° to -19.0° (c=1, in 1M HCl) |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.