5'-O-(4,4'-dimethoxytrityl)-2'-deoxyinosine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 93778-57-5 |
| Product name | 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyinosine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyinosine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyinosine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyinosine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of oligonucleotide therapeutics (e.g., antisense oligonucleotides, siRNA) | Used in solid-phase synthesis to incorporate deoxyinosine units; the DMT (4,4'-dimethoxytrityl) group protects the 5'-hydroxyl, enabling selective coupling and purification |
| Biotechnology | Preparation of modified DNA probes and primers | Employed in automated DNA synthesizers for oligonucleotide chain elongation via phosphoramidite chemistry; the DMT protecting group is removed with trichloroacetic acid after each coupling step to monitor synthesis efficiency |
| Research | Tool molecule for studying nucleic acid structure and function | Applied in fundamental studies including site-directed mutagenesis, base-pairing properties, and enzyme recognition mechanisms, leveraging its non-canonical base characteristics to model natural nucleotide variants |
Manufacturing Quality Control of 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyinosine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase chromatography with UV detection at 260 nm based on peak area comparison to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC with UV detection; identified by retention time and peak area relative to main peak. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone, ethyl acetate) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration where iodine reacts stoichiometrically with water in anhydrous medium. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, As, Hg) by inductively coupled plasma mass spectrometry after acid digestion and dilution. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after anion exchange separation. |
| Sulfate Impurity | Ion Chromatography | Separates and quantifies sulfate ions using suppressed conductivity detection after anion exchange separation. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (500–600 C) and weighing of the cooled crucible. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines hydrogen ion activity in a 1% w/v aqueous solution using calibrated glass electrode and pH meter. |
| Optical Rotation | Polarimetry | Measures specific rotation using sodium D-line light (589 nm) through a standardized solution in specified solvent and cell path length. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using controlled heating and visual observation of meniscus collapse. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic mesophilic microorganisms by filtering sample solution, culturing on soybean-casein digest agar, and counting colony-forming units. |
Technical Specifications of 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyinosine
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 215-220°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -15.0° to -19.0° (c=1, in DMF) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyinosine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyinosine
Safety Information of 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyinosine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyinosine
Industrial 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyinosine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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