4-CHLORO-7-((2-(TRIMETHYLSILYL)ETHOXY)METHYL)-7H-PYRROLO[2,3-D]PYRIMIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 941685-26-3 |
| Product name | 4-CHLORO-7-((2-(TRIMETHYLSILYL)ETHOXY)METHYL)-7H-PYRROLO[2,3-D]PYRIMIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 941685-26-3
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 941685-26-3 Supplier from China
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Industrial Applications of 941685-26-3
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate in the synthesis of anticancer agents or kinase inhibitors | Constructs the pyrrolopyrimidine scaffold via multistep organic synthesis using trimethylsilyl protecting group strategies |
| Organic Synthesis | Precursor for constructing complex heterocyclic compounds | Enables molecular modification through nucleophilic substitution and coupling reactions (e.g., Suzuki, Stille couplings) |
| Biochemical Research | Starting material for synthesizing fluorescent probes or labeling reagents | Introduces detection moieties via controlled hydrolysis or functionalization of the silyl side chain |
| Materials Science | Synthetic building block for functionalized organic semiconductor materials | Serves as a silicon-containing structural unit in the construction of polymers or optoelectronic materials |
Manufacturing Quality Control of 941685-26-3
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Using ¹H NMR, ¹³C NMR, and two-dimensional spectra (such as HSQC, HMBC) to analyze the connection relationships of hydrogen and carbon atoms in the molecule, confirming the target structure and substitution positions. |
| Molecular Weight Verification | Mass Spectrometry (MS) | Using ESI-MS or HRMS to determine the exact molecular weight, comparing with theoretical values to confirm the molecular formula and the presence of impurity adducts. |
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Using a reversed-phase column (e.g., C18) and UV detector (typically at 210–254 nm), calculating the purity of the main component by area normalization method. |
| Impurity Limit Testing | HPLC or UPLC | Establishing a gradient elution method to separate potential process impurities or degradation products, setting impurity limits (e.g., single impurity ≤ 0.5%, total impurities ≤ 1.0%). |
| Residual Solvent Testing | Gas Chromatography (GC) | Headspace injection or direct injection, using a capillary column (e.g., DB-624) and FID detector, quantifying residual organic solvents (e.g., DCM, THF). |
| Drying Loss | Drying Method / Karl Fischer Moisture Determination | Drying at 105°C until constant weight, calculating the percentage of weight loss; or using KF titration to accurately determine the moisture content in the sample. |
| Melting Point Determination | Capillary Melting Point Apparatus | Determining the temperature range for the transition from solid to liquid state, serving as a physical constant for identification and purity assessment. |
| Elemental Analysis | Elemental Analyzer (CHNS/O) | Determining the content of elements such as C, H, N, S, and comparing with theoretical values to evaluate the consistency of compound composition (usually with an error of ≤ 0.3%). |
| Chiral Purity (if applicable) | Chiral HPLC | If the molecule contains chiral centers, chiral columns are used to separate enantiomers, ensuring optical purity meets requirements (e.g., ee ≥ 99%). |
| Crystal Form Analysis (if solid) | X-ray Powder Diffraction (XRPD) | Identifying the crystal form through characteristic diffraction peaks to avoid the impact of polymorphism on stability or bioavailability. |
Technical Specifications of 941685-26-3
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 941685-26-3
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 941685-26-3
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Industrial 941685-26-3 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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