China Factory Direct
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| CAS number | 941685-27-4 |
| Product name | 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthetic intermediate for drug manufacturing | Used in the synthesis of kinase inhibitor-based anticancer drugs |
| Biochemical Research | Synthesis of biomarkers and probes | Functionalization reactions to conjugate fluorescent or other functional groups |
| Agrochemicals | Precursor compound for active pharmaceutical ingredients (APIs) | Involved in constructing heterocyclic agrochemical molecular frameworks |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, presence of caking, or visible foreign matter under natural or standard lighting conditions. |
| Identification | HPLC / FT-IR / NMR | HPLC: Compare retention time with reference standard; FT-IR: Match characteristic functional group absorption peaks; NMR: Confirm structural consistency using nuclear magnetic resonance spectroscopy. |
| Assay (Content Determination) | HPLC (External or Internal Standard Method) | Use reversed-phase high-performance liquid chromatography (e.g., C18 column) with a UV detector (typically at 254 nm or at the wavelength of maximum absorption) to quantify the main component. |
| Related Substances (Impurity Analysis) | HPLC (Gradient Elution) | Detect organic impurities in the active pharmaceutical ingredient (e.g., degradation products, by-products, residual starting materials); impurities ≥0.1% are typically required to be reported. |
| Residual Solvents | GC (Headspace Injection) | Detect volatile organic solvents used in manufacturing (e.g., methanol, ethanol, dichloromethane, DMF, tetrahydrofuran), in accordance with ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Precisely measure water content in the sample; suitable for moisture-sensitive compounds to ensure stability. |
| Sulfated Ash (Residue on Ignition) | Gravimetric Method | Weigh the residue after high-temperature ignition of the sample to evaluate inorganic impurity levels; typically limited to ≤0.1%. |
| Heavy Metals | ICP-MS or Thioglycolate Method (Chinese Pharmacopoeia) | ICP-MS offers high sensitivity and simultaneous multi-element detection; the thioglycolate method is a traditional colorimetric test for heavy metals such as lead. |
| Melting Point | Capillary Method / DSC | The capillary method is simple and fast; DSC (Differential Scanning Calorimetry) provides more accurate melting behavior and purity information. |
| Polymorph Analysis | XRD / DSC / TGA | XRD is used to identify different crystalline forms; DSC and TGA assist in determining hydration/solvation and thermal stability. |
| Particle Size Distribution | Laser Diffraction (LDI) | Evaluate the particle size distribution of solid powders, which affects solubility and formulation performance, especially important in solid dosage form development. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Purity | >=98.5% (by LC-MS) |
| Total Impurities | <=1.5% (by LC-MS) |
| Single Impurity | <=0.5% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.3% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.