China Factory Direct
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| CAS number | 942-26-7 |
| Product name | 2-(5-Chloro-1H-indol-3-yl)ethanamine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Tool compound for subtype-selective studies of serotonin (5-HT) receptors | Applied in vitro receptor binding assays and functional activity assays as a 5-HT receptor agonist or partial agonist probe |
| Neuroscience Research | Pharmacological tool for investigating neurotransmitter signaling pathway mechanisms | Used to evaluate selective activation effects on 5-HT1A, 5-HT2B, and other subtypes via brain slice electrophysiology, calcium imaging, or cAMP detection |
| Medicinal Chemistry | Starting material for structural modification of novel antidepressant and anxiolytic drug candidates | Serves as a key intermediate in synthetic steps including N-alkylation, aryl coupling, or chiral resolution to construct chloroindoleethylamine-based derivatives |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 280 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities using gradient HPLC-UV; identification and quantification based on relative retention times and response factors. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, ethyl acetate) against calibration standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine trace water content by stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element detection after acid digestion, measuring metal contaminants (e.g., Pb, Cd, Ni, Fe) via atomic emission spectroscopy. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode; endpoint detected by potential change due to AgCl precipitation. |
| pH of Aqueous Solution | pH Meter Measurement | Direct measurement of pH in a 1% w/v aqueous solution using a calibrated pH meter with glass electrode. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue after incineration at 600-700 C to determine inorganic ash content. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light through a solution to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to derive particle size distribution in dry or dispersed powder samples. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic microorganisms and absence testing for specified pathogens using selective culture media and incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow or light orange crystalline powder |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 194–198 °C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.